Independent, South San Diego hotels
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Top South San Diego Independent Hotels

The Rambler Motel
The Rambler Motel
9.0 out of 10, Wonderful, (1853)
The price is S$143
includes taxes & fees
4 Mar - 5 Mar

Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique
8.6 out of 10, Excellent, (1112)
The price is S$160
includes taxes & fees
16 Mar - 17 Mar

Quality Inn
Quality Inn
7.6 out of 10, Good, (863)
The price is S$105
includes taxes & fees
6 Mar - 7 Mar

Days Inn by Wyndham Chula Vista/San Diego
Days Inn by Wyndham Chula Vista/San Diego
6.2 out of 10, (853)
The price is S$114
includes taxes & fees
2 Mar - 3 Mar

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
7.6 out of 10, Good, (1401)
The price is S$192
includes taxes & fees
30 Mar - 31 Mar

Hotel Milagro
Hotel Milagro
7.8 out of 10, Good, (805)
The price is S$111
includes taxes & fees
6 Mar - 7 Mar

La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista
8.6 out of 10, Excellent, (1126)
The price is S$184
includes taxes & fees
16 Mar - 17 Mar

Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay
7.8 out of 10, Good, (895)
The price is S$106
includes taxes & fees
5 Mar - 6 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent Reviews in South San Diego
Recent Reviews in South San Diego

Handlery Hotel
5/5 Excellent
"Good stay for what we needed"
A verified traveller stayed at Handlery Hotel
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Areas of South San Diego
More Hotel Options in South San Diego
- Beach Resorts in South San Diego
- Budget Hotels in South San Diego
- Business Hotels in South San Diego
- Casino Hotels in South San Diego
- Family friendly Hotels in South San Diego
- Golf Hotels in South San Diego
- Hotels near Shopping Areas in South San Diego
- Hotels with Air Conditioning in South San Diego
- Hotels with Airport Shuttle in South San Diego
- Hotels with Balcony in South San Diego
- Hotels with Bars / Lounges in South San Diego
- Hotels with Breakfast in South San Diego
- Hotels with Entertainment in South San Diego
- Hotels with Gyms in South San Diego
- Hotels with Hot Tubs in South San Diego
- Hotels with Internet in South San Diego
- Hotels with Restaurants in South San Diego
- Hotels with Spa in South San Diego
- Hotels with Swimming Pools in South San Diego
- Hotels with Views in South San Diego
- Hotels with WiFi in South San Diego
- Hotels with connecting rooms in South San Diego
- Hotels with free Internet in South San Diego
- Hotels with free breakfast in South San Diego
- Hotels with free parking in South San Diego
- Hotels with free wifi in South San Diego
- Hotels with parking in South San Diego
- Hotels with shuttle in South San Diego
- Hotels with smoking rooms in South San Diego
- Luxury Hotels in South San Diego
- Pet friendly Hotels in South San Diego
- Romantic Hotels in South San Diego
More Accommodation Types in South San Diego
Explore more hotels
- Lafayette Hotel & Club
- Kings Inn San Diego
- San Diego Marriott La Jolla
- La Jolla Cove Suites
- The Horton Grand, Downtown/Gaslamp Quarter
- Wyndham Garden San Diego Near SeaWorld
- Paradise Point Resort & Spa
- The Sofia Hotel
- Best Western Plus Marina Gateway Hotel
- Manchester Grand Hyatt San Diego
- Bay Club Hotel & Marina
- Embassy Suites by Hilton San Diego La Jolla
- San Diego Mission Bay Resort
- Legacy Resort Hotel & Spa
- Marriott Marquis San Diego Marina
- Days Inn by Wyndham San Diego Hotel Circle
- The Wayfarer San Diego
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
- Alma San Diego Downtown, a Tribute Portfolio Hotel