
South San Diego Holidays
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Where to stay in South San Diego

Otay Mesa West
Even though there aren't top sights in Otay Mesa West, you can explore the larger area and take in top sights like San Ysidro Border Crossing. Jump on the metro at Iris Avenue Trolley Station to see more of the city.
Top hotels in South San Diego

Gaylord Pacific Resort & Convention Center
Reviewed on 21 Jul, 2025

The Rambler Motel
Reviewed on 18 Jul, 2025

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Reviewed on 18 Jul, 2025
What to do in South San Diego

San Diego City Lights Night Tour

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.