Southeast Missouri Hotels from from S$82

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Southeast Missouri hotels

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1008)
"Great staff "
The price is S$122
includes taxes & fees
20 Jul - 21 Jul
Drury Inn & Suites Jackson MO

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1009)
"The staff was very friendly and the hotel was very clean!"
The price is S$130
includes taxes & fees
20 Jul - 21 Jul
Drury Plaza Hotel Cape Girardeau Conference Center

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (726)
"Great place to stay convenient walking to multiple restaurants"
The price is S$158
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn Cape Girardeau I 55 East

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very good, (661)
"Property is always clean, rooms are nice."
The price is S$98
includes taxes & fees
16 Jul - 17 Jul
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (583)
"I liked that it was quiet and breakfast was good."
The price is S$137
includes taxes & fees
20 Jul - 21 Jul
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (338)
"Wonderful place to stay. Very clean and affordable!"
The price is S$152
includes taxes & fees
15 Jul - 16 Jul
The Riverview

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (41)
"Nice quiet place to stay, staff was super polite"
The price is S$147
includes taxes & fees
20 Jul - 21 Jul
Tru By Hilton Cape Girardeau

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 star property
9.4 out of 10, Exceptional, (146)
"Enjoyed our short stay, will definitely be back. "
The price is S$202
includes taxes & fees
21 Jul - 22 Jul
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very good, (877)
"Clean and convenient location "
The price is S$100
includes taxes & fees
21 Jul - 22 Jul
Super 8 by Wyndham Perryville

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (114)
"Hotel was very clean and the lady that checked us in was very friendly. "
The price is S$134
includes taxes & fees
20 Jul - 21 Jul
Fairfield Inn & Suites by Marriott Cape Girardeau

Honeysuckle Inn - Mountain View

3.0 star property
8.6 out of 10, Excellent, (297)
"It was good, but not pet friendly. "
The price is S$153
includes taxes & fees
15 Jul - 16 Jul
Honeysuckle Inn - Mountain View

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay. "
The price is S$132
includes taxes & fees
1 Aug - 2 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Great place to stay with kids "
The price is S$139
includes taxes & fees
19 Jul - 20 Jul
Pear Tree Inn Sikeston

Drury Inn & Suites Poplar Bluff

3.0 star property
9.2 out of 10, Wonderful, (884)
"I would stay again. "
The price is S$136
includes taxes & fees
20 Jul - 21 Jul
Drury Inn & Suites Poplar Bluff

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (736)
"Excellent property, great location. "
The price is S$139
includes taxes & fees
10 Aug - 11 Aug
Hampton Inn Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (771)
"Great location. Property well maintained. "
The price is S$143
includes taxes & fees
3 Aug - 4 Aug
Fairfield Inn & Suites by Marriott Poplar Bluff

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1009)
"Nice place to Stay in Cale, clean rooms and bathrooms. Safe location "
The price is S$104
includes taxes & fees
20 Jul - 21 Jul
Pear Tree Inn Cape Girardeau West

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
10.0 out of 10, Exceptional, (14)
"Nice hotel "
The price is S$177
includes taxes & fees
21 Jul - 22 Jul
Fairfield Inn & Suites by Marriott Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (361)
"Clean, great breakfast, quiet, friendly staff"
The price is S$171
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn Sikeston

Current River Inn

3.0 star property
8.2 out of 10, Very good, (142)
"This place is a treasure! So much attention to detail in the room. Comfortable, safe, quiet with wonderful staff! Highly recommend! "
The price is S$121
includes taxes & fees
29 Jul - 30 Jul
Current River Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:25 Jul - 27 Jul
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.