Southeast Missouri Hotels from from S$76

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Aug - 28 Aug
Tomorrow
28 Aug - 29 Aug
This weekend
29 Aug - 31 Aug
Next weekend
5 Sept - 7 Sept

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1004)
"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"
The price is S$133
includes taxes & fees
1 Sept - 2 Sept
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Hayti Caruthersville
Lobby

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1003)
"We enjoyed our stay."
The price is S$138
includes taxes & fees
1 Sept - 2 Sept
Drury Inn & Suites Hayti Caruthersville
Pear Tree Inn Sikeston
Lobby

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
"Very nice property Friendly helpful staff"
The price is S$114
includes taxes & fees
4 Sept - 5 Sept
Pear Tree Inn Sikeston
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1005)
"We had a last minute reservation here. The staff was very pleasant, helpful and wonderful overall!!"
The price is S$122
includes taxes & fees
3 Sept - 4 Sept
Drury Inn & Suites Jackson MO
Holiday Inn Express & Suites Perryville by IHG
Exterior

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (500)
"Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! "
The price is S$140
includes taxes & fees
31 Aug - 1 Sept
Holiday Inn Express & Suites Perryville by IHG
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby lounge

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (799)
"Hotel was very clean and the staff was friendly! I would stay again. "
The price is S$144
includes taxes & fees
4 Sept - 5 Sept
Fairfield Inn & Suites by Marriott Poplar Bluff
Postcard Cabins St. Francois
Exterior

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (29)
"Sweet cabin"
The price is S$171
includes taxes & fees
28 Aug - 29 Aug
Postcard Cabins St. Francois
Microtel Inn & Suites by Wyndham Sainte Genevieve
Premium bedding, individually furnished, desk, laptop workspace

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 star property
8.8 out of 10, Excellent, (589)
"It was a great stay. Only thimg maybe more variety or hot breakfast."
The price is S$119
includes taxes & fees
7 Sept - 8 Sept
Microtel Inn & Suites by Wyndham Sainte Genevieve
Hampton Inn Cape Girardeau I 55 East
Courtyard

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (740)
"Nice and clean hotel friendly service"
The price is S$159
includes taxes & fees
5 Sept - 6 Sept
Hampton Inn Cape Girardeau I 55 East
Shepherd Mountain Inn
Fridge, microwave, coffee/tea maker

Shepherd Mountain Inn

2.5 star property
9.2 out of 10, Wonderful, (292)
"Wonderful small town motel in a beautiful & quiet location."
Shepherd Mountain Inn
The Wildwood Hotel
Ballroom

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1563)
"Great place to stay."
The Wildwood Hotel
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Excellent place to stay "
The price is S$101
includes taxes & fees
4 Sept - 5 Sept
Pear Tree Inn Cape Girardeau Near the Medical Center
Hampton Inn Poplar Bluff
Terrace/patio

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (753)
"The room was clean, the staff were nice and breakfast bar was good "
The price is S$139
includes taxes & fees
14 Sept - 15 Sept
Hampton Inn Poplar Bluff
Crown Pointe Lodge, BW Signature Collection
Lobby

Crown Pointe Lodge, BW Signature Collection

2.5 star property
9.0 out of 10, Wonderful, (545)
"We'd stay here again."
The price is S$196
includes taxes & fees
6 Sept - 7 Sept
Crown Pointe Lodge, BW Signature Collection
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby lounge

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (125)
"The hotel was very clean and updated and the staff was super friendly and very informative!"
The price is S$135
includes taxes & fees
4 Sept - 5 Sept
Fairfield Inn & Suites by Marriott Cape Girardeau
Drury Inn & Suites Cape Girardeau
Business centre

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (985)
"Easy access and parking"
The price is S$130
includes taxes & fees
4 Sept - 5 Sept
Drury Inn & Suites Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1013)
"Very nice hotel and nice staff "
The price is S$130
includes taxes & fees
4 Sept - 5 Sept
Drury Plaza Hotel Cape Girardeau Conference Center
Century Casino & Hotel Caruthersville
1 bedroom, desk, laptop workspace, free WiFi

Century Casino & Hotel Caruthersville

2.0 star property
8.4 out of 10, Very good, (57)
"Good food and great room"
The price is S$212
includes taxes & fees
29 Aug - 30 Aug
Century Casino & Hotel Caruthersville
Holiday Inn Poplar Bluff by IHG
Breakfast, lunch, dinner served; Italian cuisine

Holiday Inn Poplar Bluff by IHG

3.0 star property
8.8 out of 10, Excellent, (672)
"Very clean and comfortable property close to dining options. Would definitely stay again "
The price is S$147
includes taxes & fees
4 Sept - 5 Sept
Holiday Inn Poplar Bluff by IHG
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (602)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is S$109
includes taxes & fees
31 Aug - 1 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:5 Sept - 7 Sept

Image gallery for Tiny Houses of French Village

Living area

Tiny Houses of French Village

2.5 star property
French Village
10/10Exceptional (3 reviews)
9% off
Price is S$733
S$366 nightly
Includes taxes & fees
Tiny Houses of French Village
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St, Farmington, MO
The price is S$76 per night from 3 Sept to 4 Sept
S$76
3 Sept - 4 Sept
includes taxes & fees
8/10 Very Good! (1,003 reviews)

Hotels in Southeast Missouri with star rating

Hotels in Southeast Missouri with star rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia