Photo by Ryan Coleman

Sikeston Hotels from from S$102

March 2025

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Top 10 trending Sikeston hotels

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1000)
"The Drury was excellent. The room was sapcious and very clean. Breakfast in the morning was great. Easy access to the interstate."
The price is S$142
includes taxes & fees
31 Mar - 1 Apr
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1003)
"The property was clean and quiet. The breakfast options were very good."
The price is S$127
includes taxes & fees
30 Mar - 31 Mar
Drury Inn & Suites Jackson MO

The Riverview

3.5 star property
9.2 out of 10, Wonderful, (195)
"Beautiful rooms!"
The price is S$142
includes taxes & fees
1 Apr - 2 Apr
The Riverview

Tru By Hilton Cape Girardeau

2.5 star property
10.0 out of 10, Exceptional, (2)
"Clean new hotel, modern look and feel. Comfortable beds. Convenient room layout with lots of outlets, USB ports, several lamps near bed, brightly lit bathroom, great shower, hooks on wall to hang things, small fridge. Cookies offered at our check-in were good. Billiards table in lobby. Nice selection for the included breakfast (yogurt with granola, bagels, scrambked eggs, sausage, pancakes, fruit, cereal). Good coffee, tea, and lemon water available in lobby 24 hrs. Close to several restaurants...
The price is S$154
includes taxes & fees
6 Apr - 7 Apr
Tru By Hilton Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

2.5 star property
9.0 out of 10, Wonderful, (519)
"We love this hotel. We stay here every time we visit our daughter at SEMO."
The price is S$121
includes taxes & fees
27 Mar - 28 Mar
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"It was small room but was okay "
The price is S$102
includes taxes & fees
31 Mar - 1 Apr
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Staff was very friendly and hotel was very clean. Only problem was bed was hard."
The price is S$109
includes taxes & fees
31 Mar - 1 Apr
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Very nice hotel. Except when we went to the hot tub, there was a bowel movement in the water. Didn't notice till we got out. Reported to hotel staff."
The price is S$131
includes taxes & fees
1 Apr - 2 Apr
Pear Tree Inn Sikeston

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (910)
"Staff was polite and very helpful and attentive. Will stay here the next time I’m passing through."
The price is S$149
includes taxes & fees
31 Mar - 1 Apr
Drury Inn & Suites Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (94)
"Very clean and updated"
The price is S$140
includes taxes & fees
10 Apr - 11 Apr
Fairfield Inn & Suites by Marriott Cape Girardeau

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1002)
"Night time snacks were a perfect dinner option for us! Great breakfast to get us on the road for a long travel day. Very nice accommodations. "
The price is S$152
includes taxes & fees
6 Apr - 7 Apr
Drury Inn & Suites Sikeston, MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Needed an overnight traveling back home. Nabbed this great room. Just wish that I would have been there a bit lo ger to enjoy it. Super hot shower with great water pressure was also very welcome. The macadamia nut cookies were awesome!! "
The price is S$156
includes taxes & fees
6 Apr - 7 Apr
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (404)
"Had a great visit to Cape. Lovely place to stay the night. Convenient to shoppin, food and fun!"
The price is S$190
includes taxes & fees
6 Apr - 7 Apr
Courtyard by Marriott Cape Girardeau Downtown

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (696)
"The staff were friendly and the hotel was clean and conveniently located to the sportsplex. "
The price is S$165
includes taxes & fees
6 Apr - 7 Apr
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (325)
"Friendly staff, comfortable beds, spacious room (313). "
The price is S$166
includes taxes & fees
6 Apr - 7 Apr
Hampton Inn Sikeston

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very good, (748)
"The appliances in the room are a nice touch "
The price is S$137
includes taxes & fees
1 Apr - 2 Apr
Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (399)
"Clean "
The price is S$185
includes taxes & fees
13 Apr - 14 Apr
Holiday Inn Express & Suites Sikeston Southwest by IHG

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very good, (692)
"Room looked great when we got there. There was a few things that needed attention. I left them a note."
The price is S$126
includes taxes & fees
27 Mar - 28 Mar
Comfort Suites Jackson-Cape Girardeau

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very good, (1003)
"liked the person that checked us in came and showed us how to get tv on "
The price is S$138
includes taxes & fees
20 Apr - 21 Apr
Best Western Plus Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.

What's the best family accommodation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your family trip. Also, children of all ages will enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What's the best LGBTQ-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Drury Inn & Suites Sikeston, MO and Holiday Inn Express & Suites Sikeston Southwest by IHG are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best dog-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Days Inn and Suites by Wyndham Sikeston. See more pet-friendly hotel accommodations in Sikeston.

What's the best hotel for a golf holiday in Sikeston?

Travel Inn & Suites is a hotel featuring free breakfast and free WiFi, and it's a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip. See more golf hotels in Sikeston.

What are some hotels with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. View all hotels with pools in Sikeston.

What is the best spa hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top spa hotel featuring a pool and a fitness centre. See all spa hotels in Sikeston.

What is staying in Sikeston like?

Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.

What is there to see in Sikeston?

Favourite places to visit include Sikeston Depot Museum, Boot Heel Golf Club and The Book Bug. Additionally, you might want to add Central Park to your itinerary. Take a look at what more there is to see and do in Expedia's Sikeston guide.

What's the seasonal weather in Sikeston?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.

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