Photo by Southernmost Illinois Tourism Bureau

Southern Illinois Hotels from from S$75

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1394)
"Nice rooms, enjoyed our stay"
The price is S$137
includes taxes & fees
10 Aug - 11 Aug
Drury Plaza Hotel Mt. Vernon

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (832)
"Very good place to stay"
The price is S$122
includes taxes & fees
27 Jul - 28 Jul
SureStay Hotel by Best Western Whittington Rend Lake

Super 8 by Wyndham Grayville

2.0 star property
8.2 out of 10, Very good, (432)
"Very calm and quiet stay and close to the Garden of Gods park"
The price is S$98
includes taxes & fees
27 Jul - 28 Jul
Super 8 by Wyndham Grayville

Cobblestone Inn & Suites - Altamont

2.5 star property
9.6 out of 10, Exceptional, (731)
"Always a great place with comfortable rooms."
Cobblestone Inn & Suites - Altamont

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (97)
"Perfect stay! "
The price is S$146
includes taxes & fees
22 Jul - 23 Jul
The Principal Hotel

Quality Inn Effingham

2.5 star property
8.4 out of 10, Very good, (886)
"I would stay here again "
The price is S$130
includes taxes & fees
15 Aug - 16 Aug
Quality Inn Effingham

Days Inn & Suites by Wyndham Casey

2.0 star property
7.4 out of 10, Good, (746)
"Great location and a quite place to stay and relax "
The price is S$107
includes taxes & fees
27 Jul - 28 Jul
Days Inn & Suites by Wyndham Casey

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1008)
"Clean and nice property with nice staff"
The price is S$147
includes taxes & fees
10 Aug - 11 Aug
Drury Inn & Suites Marion

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (455)
"Excellent stay!"
The price is S$148
includes taxes & fees
3 Aug - 4 Aug
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Best Western Plus Parkside Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (284)
"Very clean! Staff is super friendly! "
The price is S$169
includes taxes & fees
27 Jul - 28 Jul
Best Western Plus Parkside Inn & Suites

Super 8 by Wyndham O'Fallon

2.0 star property
7.4 out of 10, Good, (1018)
"This is the first hotel I've been to where the beds are comfortable and the pillows firm enough."
The price is S$75
includes taxes & fees
27 Jul - 28 Jul
Super 8 by Wyndham O'Fallon

Economy Inn & Suites

2.0 star property
8.4 out of 10, Very good, (45)
"Very clean room and excellent reception. "
The price is S$107
includes taxes & fees
27 Jul - 28 Jul
Economy Inn & Suites

Best Western Marion Hotel

2.5 star property
8.2 out of 10, Very good, (1003)
"Very clean nice rooms friendly staff"
The price is S$121
includes taxes & fees
27 Jul - 28 Jul
Best Western Marion Hotel

Harrah's Metropolis Hotel & Casino

3.5 star property
8.4 out of 10, Very good, (1004)
"Great stay"
The price is S$176
includes taxes & fees
22 Jul - 23 Jul
Harrah's Metropolis Hotel & Casino

Baymont by Wyndham Marion

2.5 star property
8.4 out of 10, Very good, (1037)
"Great hotel , stayed for a month for work and was please with the staff friendliness and attentiveness "
The price is S$139
includes taxes & fees
27 Jul - 28 Jul
Baymont by Wyndham Marion

Baymont by Wyndham Chester IL

2.5 star property
8.6 out of 10, Excellent, (321)
"Great quick clean stay"
The price is S$119
includes taxes & fees
14 Aug - 15 Aug
Baymont by Wyndham Chester IL

Super 8 by Wyndham Okawville

2.0 star property
7.2 out of 10, Good, (284)
"Lots of parking for truck and trailer. "
The price is S$95
includes taxes & fees
28 Jul - 29 Jul
Super 8 by Wyndham Okawville

La Quinta Inn & Suites by Wyndham Effingham

3.0 star property
9.2 out of 10, Wonderful, (1005)
"Nice stay"
The price is S$146
includes taxes & fees
27 Jul - 28 Jul
La Quinta Inn & Suites by Wyndham Effingham

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1005)
"Great place to stay "
The price is S$164
includes taxes & fees
27 Jul - 28 Jul
Drury Inn & Suites St. Louis Collinsville

Country Inn & Suites by Radisson, Effingham, IL

2.5 star property
8.8 out of 10, Excellent, (1006)
"Nice place"
The price is S$148
includes taxes & fees
27 Jul - 28 Jul
Country Inn & Suites by Radisson, Effingham, IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:1 Aug - 3 Aug
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Southern Illinois

Experience the family-friendly area of Southern Illinois—live music, an opera house and sights from Jefferson County Fairgrounds to Salem Fairgrounds.

Southern Illinois featuring a sunset, forests and landscape views
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews