Photo by Michele Butts

Find Luxury Hotels in La Mesa

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Top Luxury Hotels in La Mesa

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1002)
"Overall felt very aae and had no problems with noise or any unruly fellow hotel clients or outside the building. Staff very friendly and helpful."
The price is S$156
includes taxes & fees
1 Dec - 2 Dec
Best Western Plus La Mesa San Diego

Motel 6 La Mesa, CA

2.0 star property
7.2 out of 10, Good, (1013)
"This is my second time staying at this location and it was very nice and quiet. The staff are very professional and easy to communicate with. They’re very helpful and accommodating. This is my go to spot when I come to San Diego. "
The price is S$210
includes taxes & fees
1 Dec - 2 Dec
Motel 6 La Mesa, CA

Heritage Inn La Mesa

2.0 star property
6.2 out of 10, (1013)
"Nothing "
The price is S$90
includes taxes & fees
8 Dec - 9 Dec
Heritage Inn La Mesa

Holiday Inn Express La Mesa Near SDSU, an IHG Hotel

2.5 star property
8.2 out of 10, Very good, (226)
"The overall stay was great; however, they failed to mention that there was a parking fee for each day prior to booking and that the pet deposit was for each day instead of one fee. When we got our bill we were less than thrilled to see extra fees on this."
The price is S$169
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express La Mesa Near SDSU, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beautiful view of the beach with palm trees

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Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to La Mesa?
Use Expedia and let us help you arrange a flight to San Diego, CA (SEE-Gillespie Field) airport or San Diego, CA (MYF-Montgomery Field) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you’d like to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that La Mesa has to offer. During your visit, you might want to enjoy the entertainment which La Mesa is known for.
How many luxury hotels are there in La Mesa?
Lie in the lap of luxury during your getaway to La Mesa in one of Expedia’s 6 luxury hotels.
When can I expect good weather in La Mesa?
Planning for the weather is an important factor for making your trip to La Mesa a success, especially when you’re splurging. The hottest months are usually August and September, with an average temperature of 22°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for La Mesa is 308 mm.
What's there to see and do in La Mesa?
Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo and Mission Bay. If you have a bit of extra time while you’re in the area, you might want to check out Mission Beach and San Ysidro Border Crossing.
How can I get around La Mesa?
It’s easier to get around town in style when you know your options. Nearby metro stations include La Mesa Boulevard Station, Spring St Trolley Station and 70th St. Trolley Station.