What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center .

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 62 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.

Top 10 South Main Hotels of 2025

Top 10 Hotels in South Main

"Great location close to nrg stadium rooms were good and breakfast was great"

includes taxes & fees

20 Jul - 21 Jul

"Perfect location to be walking distance to NRG. "

includes taxes & fees

3 Jul - 4 Jul

1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated

"Vanessa and everyone at front desk was extremely accommodating & gracious. The BEST out of the whole stay. Thank yall so much "

includes taxes & fees

16 Jul - 17 Jul

"Convenient to where I wanted to be staff was nice too"

includes taxes & fees

9 Jul - 10 Jul

"Great property "

includes taxes & fees

3 Jul - 4 Jul

"totally recommend staying here! very nice, clean, safe place! "

includes taxes & fees

12 Jul - 13 Jul

Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

"It was a beautiful stay "

includes taxes & fees

3 Jul - 4 Jul

"Would stay again ANY day!!"

includes taxes & fees

13 Jul - 14 Jul

"We really enjoyed our stay "

includes taxes & fees

31 Jul - 1 Aug

Breakfast, lunch, brunch served; American cuisine, garden views

"Peaceful and relaxing stay."

includes taxes & fees

6 Jul - 7 Jul

"Wonderful hotel and great breakfast."

includes taxes & fees

3 Jul - 4 Jul

"Great hotel and location "

includes taxes & fees

17 Jul - 18 Jul

"Lovely hotel"

includes taxes & fees

4 Jul - 5 Jul

Premium bedding, desk, iron/ironing board, free WiFi

"Nice place to stay"

"Very convenient location close to downtown very friendly staff, clean room I will recommend this hotel to my family "

includes taxes & fees

9 Jul - 10 Jul

"Enjoyed my stay...the staff members are all super welcoming and accommodating "

includes taxes & fees

31 Jul - 1 Aug

"We loved the pool and the breakfast "

includes taxes & fees

3 Jul - 4 Jul

"This hotel is very clean and staff is extremely helpful and welcoming."

includes taxes & fees

5 Jul - 6 Jul

"Good for a quick overnight stay! "

includes taxes & fees

10 Jul - 11 Jul

"I really enjoyed my stay. The bed was sooooo soft. The breakfast was pretty good as well. The employees at the front desk were so sweet. Great place to stay. "

includes taxes & fees

17 Jul - 18 Jul

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.

Discovery Green showing a square or plaza, a city and a skyscraper

Downtown Houston

3 out of top 10 points of interest in this area

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

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The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

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Texas Medical Center

1 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

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Menil Collection showing interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

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Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

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Recent Reviews in South Main

5/5 Excellent

"Nice hotel, very clean and with friendly staff. Buffalo Bayou was a simple but great start to the day, and they were very accommodating. The pool area was nice too. Would recommend!"

A verified traveller stayed at The Whitehall Houston

Posted 1 day ago