Hotels in South Central Houston

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Jul - 13 Jul
Tomorrow
13 Jul - 14 Jul
Next weekend
18 Jul - 20 Jul
In two weeks
25 Jul - 27 Jul

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in South Central Houston

Houston Marriott Medical Center/Museum District
Relax in a stylish lounge area with a curved sofa, armchairs, and a coffee table.

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1005)
"Peaceful and relaxing stay."
The price is S$269
includes taxes & fees
8 Aug - 9 Aug
Houston Marriott Medical Center/Museum District
Hotel Zaza Houston Museum District
Enjoy city views from the large window, relax in the plush armchair, and unwind with a good night's sleep on the classic bed.

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1718)
"Great stay!"
The price is S$296
includes taxes & fees
10 Aug - 11 Aug
Hotel Zaza Houston Museum District
Americas Best Value Inn Medical Center Downtown
Two beds with matching headboards and footboards, a nightstand, and a bedside table with a lamp.

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1005)
"Highly recommended.. I will stay again."
The price is S$124
includes taxes & fees
14 Jul - 15 Jul
Americas Best Value Inn Medical Center Downtown
Hilton Houston Plaza/Medical Center
Relax by the pool surrounded by lounge chairs and sunbeds, with a clear view of the adjacent building.

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very good, (1436)
"Conveniently located and excellent property. "
The price is S$155
includes taxes & fees
20 Jul - 21 Jul
Hilton Houston Plaza/Medical Center
The Westin Houston Medical Center/Museum District
Relax by the rooftop pool, surrounded by lounge chairs and umbrellas.

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1021)
"Great place to stay "
The price is S$230
includes taxes & fees
19 Jul - 20 Jul
The Westin Houston Medical Center/Museum District
La Maison in Midtown an urban B&B
Residents enjoy balconies and a secure, well-maintained outdoor space.

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (511)
"Nice property we are enjoying our stay. "
The price is S$268
includes taxes & fees
14 Jul - 15 Jul
La Maison in Midtown an urban B&B
Hilton University of Houston
Two large beds with grey headboards and white bedding, a desk and chair, and a balcony with city views.

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (839)
"Awesome Hotel. "
The price is S$241
includes taxes & fees
19 Jul - 20 Jul
Hilton University of Houston
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Enjoy a diverse selection of food at our self-service buffet.

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.2 out of 10, Very good, (380)
"Very nice place clean nice towels good shower"
The price is S$161
includes taxes & fees
20 Jul - 21 Jul
DoubleTree by Hilton Houston Medical Center Hotel & Suites
InterContinental Houston by IHG
Enjoy meals in a beautifully decorated dining area with a vibrant mural and elegant table setting.

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1003)
"Great Place"
The price is S$234
includes taxes & fees
20 Jul - 21 Jul
InterContinental Houston by IHG
Wanderstay Boutique Hotel
1 bedroom, in-room safe, individually decorated, individually furnished

Wanderstay Boutique Hotel

2.0 star property
9.8 out of 10, Exceptional, (39)
"Great stay!"
The price is S$189
includes taxes & fees
14 Jul - 15 Jul
Wanderstay Boutique Hotel
Modern Cozy Home with King Bed
Enjoy cooking in this well-equipped kitchen with a stainless steel refrigerator, oven, and ample counter space.

Modern Cozy Home with King Bed

3.5 star property
9.6 out of 10, Exceptional, (16)
"Everything was great, beautiful view! "
The price is S$445
includes taxes & fees
29 Jul - 30 Jul
Modern Cozy Home with King Bed
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Enjoy a balcony with potted plants and a view of the pool surrounded by a garden.

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (190)
"This was a wonderful place to stay!!"
The price is S$321
includes taxes & fees
14 Jul - 15 Jul
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Paradise Palace Best Rooftop in HTX w Hot Tub
Enjoy a meal in the kitchen with a central island and oven, microwave, and large window offering a view of the outdoors.

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
The price is S$828
includes taxes & fees
14 Jul - 15 Jul
Paradise Palace Best Rooftop in HTX w Hot Tub
The Oasis Checkmate HTX Rooftop
Relax on the rooftop with a game of chess, surrounded by a beautiful lattice structure and a potted plant.

The Oasis Checkmate HTX Rooftop

3.0 star property
10.0 out of 10, Exceptional, (2)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
The Oasis Checkmate HTX Rooftop
Luxury Med Center Fully Equipped King Sized Bed Condos
Features a well-lit kitchen with stainless steel appliances, black cabinetry, and a tiled backsplash.

Luxury Med Center Fully Equipped King Sized Bed Condos

4.0 star property
8.4 out of 10, Very good, (92)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
The price is S$361
includes taxes & fees
27 Jul - 28 Jul
Luxury Med Center Fully Equipped King Sized Bed Condos
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Relax in the hotel's spacious lobby, featuring a mezzanine level, comfortable seating areas, and a flat-screen TV.

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1007)
"Very clean and peaceful place to stay close to the hospital 🏥 "
The price is S$122
includes taxes & fees
18 Jul - 19 Jul
Extended Stay America Suites Houston Med Ctr Braeswood Bl
The Green Haus Luxxe Cabana Rooftop Retreat
Relax in a shaded outdoor space with a sofa set, wicker chair, and hanging chair, surrounded by a cityscape.

The Green Haus Luxxe Cabana Rooftop Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The Green Haus Luxxe Cabana Rooftop Retreat
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Enjoy cooking in this well-lit kitchen with a refrigerator, microwave, double oven, and sleek cabinetry.

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
The price is S$742
includes taxes & fees
15 Jul - 16 Jul
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Rodeway Inn & Suites Houston near Medical Center
Compact living space with a kitchenette, sofa, and coffee table.

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
6.2 out of 10, (470)
"It was affordable and comfortable. "
The price is S$84
includes taxes & fees
14 Jul - 15 Jul
Rodeway Inn & Suites Houston near Medical Center
Southmore Boulevard Motel
Relax in a spacious room with a large bed, desk, and mirror.

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (216)
"Good area"
The price is S$97
includes taxes & fees
14 Jul - 15 Jul
Southmore Boulevard Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
Discovery Green showing a square or plaza, a city and a skyscraper
Downtown Houston map

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria map

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center map

Texas Medical Center

2 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection showing interior views and art
Montrose map

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Houston showing a city and a skyscraper
Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Frequently asked questions

What's it like in South Central Houston?

Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighbourhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other top choices in the neighbourhood include La Maison in Midtown an urban B&B and The Westin Houston Medical Center/Museum District.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1151 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.

What is there to do around this Houston neighbourhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Bagby Dog Park. Houston Zoo and Children's Museum of Houston are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station.