There are several airlines that operate frequent flights from Portland (PDX) to San Francisco (SFO) including

• Alaska Airlines with 326 flights a week
• Delta Air Lines with 58 flights a week
• United Airlines with 52 flights a week
• Emirates with 32 flights a week
• American Airlines with 32 flights a week

The earliest flight leaves Portland Intl. Airport at 05:10 and arrives at San Francisco Intl. Airport at 00:05. The last flight of the day departs Portland at 22:20 and arrives at San Francisco at 23:31.

The flight distance from Portland to San Francisco is about 890 km, the shortest flight is 01 hours 40 minutes with .

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