There are several airlines that operate frequent flights from Manila (MNL) to San Francisco (SFO) including

• Philippine Airlines with 115 flights a week
• Cathay Dragon with 36 flights a week
• Cathay Pacific with 35 flights a week
• All Nippon Airways with 26 flights a week
• EVA Airways with 24 flights a week

The earliest flight leaves Ninoy Aquino Intl. Airport at 20:45 and arrives at San Francisco Intl. Airport at 18:10. The last flight of the day departs Manila at 22:00 and arrives at San Francisco at 20:00.

The flight distance from Manila to San Francisco is about 11289 km, the shortest flight is 12 hours 10 minutes with Philippine Airlines.

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