Photo by Hideki Yamagata

Hotels in San Francisco

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
10 Jul - 11 Jul
Tomorrow
11 Jul - 12 Jul
This weekend
11 Jul - 13 Jul
Next weekend
18 Jul - 20 Jul

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in San Francisco

Ramada Plaza By Wyndham Panama Punta Pacífica
Relax in a serene outdoor space with a patio, seating areas, and a small pool.

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1007)
"Great and easy stay. Would stay again. "
The price is S$143
includes taxes & fees
1 Aug - 2 Aug
Ramada Plaza By Wyndham Panama Punta Pacífica
Courtyard by Marriott Panama Multiplaza Mall
Indulge in a diverse spread of fresh fruits, vegetables, and condiments at our buffet.

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1002)
"Amazing hotel"
The price is S$196
includes taxes & fees
12 Jul - 13 Jul
Courtyard by Marriott Panama Multiplaza Mall
Aloft Panama
Experience the sleek, modern design of this hotel, featuring a striking vertical structure with a grid-patterned facade and a welcoming entrance.

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (819)
"Great location "
The price is S$152
includes taxes & fees
19 Jul - 20 Jul
Aloft Panama
Sheraton Grand Panama
Terrace/patio

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (891)
"A great stay. "
The price is S$163
includes taxes & fees
18 Jul - 19 Jul
Sheraton Grand Panama
Boutique Apartments Panamá Coco del Mar
Relax on the spacious deck with a panoramic view of the city skyline and water.

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.4 out of 10, Good, (105)
"Amazing and spacious apartment with amazing views! Great for families and or groups! Great price! The only downside, one of the beds was very uncomfortable to sleep. "
The price is S$223
includes taxes & fees
16 Jul - 17 Jul
Boutique Apartments Panamá Coco del Mar
Megapolis Hotel Panamá
Standing tall with a grid-like facade and numerous windows, this high-rise building showcases a dynamic design.

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very good, (944)
"The hotel is beautiful and our suite was very spacious. Felt like home away from home. "
The price is S$179
includes taxes & fees
18 Jul - 19 Jul
Megapolis Hotel Panamá
San Francisco by Wynwood House
Enjoy a city view from the comfort of this stylish room, featuring a round table, sofa, and flat-screen TV.

San Francisco by Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (39)
"Very neat and lots of restaurants in the area. Mall is close by."
The price is S$166
includes taxes & fees
20 Jul - 21 Jul
San Francisco by Wynwood House
Plaza Paitilla Inn Hotel
Experience the dynamic cityscape with a blend of urban and natural elements.

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2066)
"Great stay!"
The price is S$213
includes taxes & fees
13 Jul - 14 Jul
Plaza Paitilla Inn Hotel
JW Marriott Panama
Relax in a tranquil setting surrounded by a clear pool and palm trees.

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1010)
"We truly enjoyed our stay at this hotel and will be back in future! "
The price is S$286
includes taxes & fees
25 Jul - 26 Jul
JW Marriott Panama
Decapolis Hotel Panama City
Experience the city from a modern high-rise building with panoramic views.

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1232)
"Wonderful stay. "
The price is S$131
includes taxes & fees
17 Jul - 18 Jul
Decapolis Hotel Panama City
Residence Inn by Marriott Panama City
Relax by the serene pool surrounded by a high-rise building complex with stunning views.

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (481)
"Great location clean "
The price is S$190
includes taxes & fees
18 Jul - 19 Jul
Residence Inn by Marriott Panama City
Boutique Apartments Atlapa
Relax by the rooftop pool with a stunning city view.

Boutique Apartments Atlapa

3.0 star property
7.4 out of 10, Good, (14)
"The area was great, just a short walk to many great places to eat and the supermarket. We enjoyed the facilities and the staff was always friendly and easy to deal with/talk to. Fantastic place to stay."
Boutique Apartments Atlapa
Las Americas Golden Tower Panama
Experience the sleek lobby with a curved glass railing and a striking column, offering views of the city.

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1002)
"Great stay"
The price is S$203
includes taxes & fees
5 Aug - 6 Aug
Las Americas Golden Tower Panama
Wanders & Yoo
Relax by the pool with a view of the city.

Wanders & Yoo

4.0 star property
9.0 out of 10, Wonderful, (8)
"Cool and modern condos, great location and views."
The price is S$561
includes taxes & fees
1 Aug - 2 Aug
Wanders & Yoo
Crowne Plaza Panama Airport by IHG
Relax by the pool surrounded by comfortable lounge chairs and umbrellas.

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very good, (2145)
"Great place!"
The price is S$157
includes taxes & fees
19 Jul - 20 Jul
Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive
Relax by the pool surrounded by lush greenery and palm trees, with lounge chairs and umbrellas at your disposal.

Dreams Playa Bonita Panama - All Inclusive

4.0 star property
7.4 out of 10, Good, (1002)
"Excellent service and staff"
The price is S$314
includes taxes & fees
1 Aug - 2 Aug
Dreams Playa Bonita Panama - All Inclusive
Central Hotel Panama Casco Viejo
Experience the grandeur of our lobby, featuring a soaring ceiling, elegant seating areas, and beautiful artwork.

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (933)
"Property was in a great location and the the breakfast was really good."
Central Hotel Panama Casco Viejo
The Westin Playa Bonita Panama
Relax by the infinity pool overlooking the ocean and a small island.

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very good, (1006)
"Clean large rooms, beautiful beach and pools, many dining options and great service "
The price is S$217
includes taxes & fees
1 Aug - 2 Aug
The Westin Playa Bonita Panama
Hotel Riu Plaza Panama
Relax by the pool surrounded by lush greenery and modern architecture.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4087)
"My stay was great and the breakfast was delicious!"
The price is S$168
includes taxes & fees
13 Jul - 14 Jul
Hotel Riu Plaza Panama
Hospedium Princess Hotel Panama
Relax by the rooftop pool with city skyline views and lounge in style.

Hospedium Princess Hotel Panama

3.5 star property
7.6 out of 10, Good, (548)
"Very nice and friendly staff"
The price is S$60
includes taxes & fees
15 Jul - 16 Jul
Hospedium Princess Hotel Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
Casco Viejo map

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista map

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo map

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla map

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Calidonia map

Calidonia

1 out of top 10 points of interest in this area

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza By Wyndham Panama Punta Pacífica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Residence Inn by Marriott Panama City and Decapolis Hotel Panama City.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 181 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.