Photo by Hideki Yamagata

Hotels in San Francisco

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in San Francisco

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1000)
"Great and easy stay. Would stay again. "
The price is S$142
includes taxes & fees
1 Aug - 2 Aug
Ramada Plaza By Wyndham Panama Punta Pacífica

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1002)
"Amazing hotel"
The price is S$175
includes taxes & fees
19 Jul - 20 Jul
Courtyard by Marriott Panama Multiplaza Mall

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (815)
"Great location "
The price is S$143
includes taxes & fees
19 Jul - 20 Jul
Aloft Panama

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (887)
"A great stay. "
The price is S$154
includes taxes & fees
18 Jul - 19 Jul
Sheraton Grand Panama

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.4 out of 10, Good, (101)
"Amazing and spacious apartment with amazing views! Great for families and or groups! Great price! The only downside, one of the beds was very uncomfortable to sleep. "
The price is S$219
includes taxes & fees
6 Jul - 7 Jul
Boutique Apartments Panamá Coco del Mar

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very good, (935)
"The hotel is beautiful and our suite was very spacious. Felt like home away from home. "
The price is S$178
includes taxes & fees
6 Jul - 7 Jul
Megapolis Hotel Panamá

San Francisco by Wynwood House

4.0 star property
9.6 out of 10, Exceptional, (38)
"Very neat and lots of restaurants in the area. Mall is close by."
The price is S$169
includes taxes & fees
4 Aug - 5 Aug
San Francisco by Wynwood House

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2053)
"Great place! "
The price is S$212
includes taxes & fees
6 Jul - 7 Jul
Plaza Paitilla Inn Hotel

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1003)
"Very beautiful and comfortable place to stay, with all the amenities."
The price is S$285
includes taxes & fees
18 Jul - 19 Jul
JW Marriott Panama

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1222)
"Wonderful stay. "
The price is S$130
includes taxes & fees
6 Jul - 7 Jul
Decapolis Hotel Panama City

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (478)
"Great location clean "
The price is S$189
includes taxes & fees
18 Jul - 19 Jul
Residence Inn by Marriott Panama City

Boutique Apartments Atlapa

3.0 star property
7.4 out of 10, Good, (14)
"The area was great, just a short walk to many great places to eat and the supermarket. We enjoyed the facilities and the staff was always friendly and easy to deal with/talk to. Fantastic place to stay."
Boutique Apartments Atlapa

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1000)
"Great stay"
The price is S$214
includes taxes & fees
6 Jul - 7 Jul
Las Americas Golden Tower Panama

Wanders & Yoo

4.0 star property
9.0 out of 10, Wonderful, (8)
"Cool and modern condos, great location and views."
The price is S$565
includes taxes & fees
1 Aug - 2 Aug
Wanders & Yoo

Dreams Playa Bonita Panama - All Inclusive

4.0 star property
7.4 out of 10, Good, (1006)
"Excellent service and staff"
The price is S$312
includes taxes & fees
1 Aug - 2 Aug
Dreams Playa Bonita Panama - All Inclusive

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very good, (2125)
"Great place!"
The price is S$168
includes taxes & fees
26 Jul - 27 Jul
Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (930)
"Property was in a great location and the the breakfast was really good."
Central Hotel Panama Casco Viejo

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very good, (1001)
"Pool was great"
The price is S$208
includes taxes & fees
11 Jul - 12 Jul
The Westin Playa Bonita Panama

Hospedium Princess Hotel Panama

3.5 star property
7.6 out of 10, Good, (545)
"Very nice and friendly staff"
The price is S$59
includes taxes & fees
13 Jul - 14 Jul
Hospedium Princess Hotel Panama

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1003)
"Hotel very clean and the staff was excellent "
The price is S$114
includes taxes & fees
24 Jul - 25 Jul
TRYP by Wyndham Panamá Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
Casco Viejo map

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista map

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo map

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Calidonia map

Calidonia

1 out of top 10 points of interest in this area

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Punta Paitilla map

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza By Wyndham Panama Punta Pacífica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Residence Inn by Marriott Panama City and Decapolis Hotel Panama City.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 181 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.