Hotels near Mississippi River

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels Near Mississippi River

The Eagles Nest Inn

3.0 star property
9.2 out of 10, Wonderful, (7)
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."
The price is S$119
includes taxes & fees
31 Jul - 1 Aug
The Eagles Nest Inn

River's Edge Motel

2.0 star property
9.0 out of 10, Wonderful, (332)
"Great clean place to stay with friendly staff"
The price is S$116
includes taxes & fees
23 Jul - 24 Jul
River's Edge Motel

Riverside Inn Hannibal

2.5 star property
9.4 out of 10, Exceptional, (127)
"Excellent service, room, and location."
The price is S$235
includes taxes & fees
18 Aug - 19 Aug
Riverside Inn Hannibal

Lighthouse Inn & Suites

4.0 star property
9.0 out of 10, Wonderful, (11)
"Location is excellent! Close to historic downtown but far enough away to be quiet and peaceful! Very clean and decor is wonderful!"
The price is S$218
includes taxes & fees
27 Jul - 28 Jul
Lighthouse Inn & Suites

Sleep Inn & Suites

2.5 star property
9.6 out of 10, Exceptional, (1006)
"Great stay!"
The price is S$172
includes taxes & fees
17 Aug - 18 Aug
Sleep Inn & Suites

Garden House Bed and Breakfast

2.0 star property
8.6 out of 10, Excellent, (22)
"A beautiful 19th century mansion, decorated in period. Quiet and comfortable."
The price is S$149
includes taxes & fees
7 Aug - 8 Aug
Garden House Bed and Breakfast

Best Western On The River

2.5 star property
8.6 out of 10, Excellent, (1006)
"Excellent and friendly staff!! Good breakfast as well!"
The price is S$187
includes taxes & fees
27 Jul - 28 Jul
Best Western On The River

Motel 6 Hannibal, MO

2.0 star property
7.6 out of 10, Good, (1002)
"Large room's and very nice staff."
The price is S$81
includes taxes & fees
27 Jul - 28 Jul
Motel 6 Hannibal, MO

Quality Inn & Suites Hannibal

2.5 star property
7.8 out of 10, Good, (1004)
"Good location, very welcoming, room was comfortable & breakfast was tasty. "
The price is S$165
includes taxes & fees
27 Jul - 28 Jul
Quality Inn & Suites Hannibal

Super 8 by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (1003)
"Nice place, easy to find. "
The price is S$94
includes taxes & fees
29 Jul - 30 Jul
Super 8 by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (177)
"Just needed for one night and it was ok staying there. Bed fairly good and good water pressure "
The price is S$103
includes taxes & fees
27 Jul - 28 Jul
Days Inn by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2.0 star property
7.0 out of 10, Good, (125)
"Old-style looks clean "
The price is S$91
includes taxes & fees
23 Jul - 24 Jul
Howard Johnson BY Wyndham Hannibal

Town & Country Inn and Suites

2.5 star property
9.2 out of 10, Wonderful, (844)
"Very friendly staff"
The price is S$174
includes taxes & fees
28 Jul - 29 Jul
Town & Country Inn and Suites

Baymont by Wyndham Hannibal

2.5 star property
6.2 out of 10, (676)
"Very good breakfast, nice heated indoor pool, good exercise room, friendly staff. Highly recommended."
The price is S$101
includes taxes & fees
23 Jul - 24 Jul
Baymont by Wyndham Hannibal

Stoney Creek Inn Quincy

2.0 star property
8.8 out of 10, Excellent, (1006)
"Great stay at a great price"
Stoney Creek Inn Quincy

Heritage Hotel Quincy

2.0 star property
8.8 out of 10, Excellent, (125)
"Renovated hotel, clean, nice staff. "
The price is S$130
includes taxes & fees
23 Jul - 24 Jul
Heritage Hotel Quincy

Quality Inn & Suites Quincy - Downtown

2.5 star property
8.8 out of 10, Excellent, (428)
"Good experience but bed too firm."
The price is S$174
includes taxes & fees
20 Aug - 21 Aug
Quality Inn & Suites Quincy - Downtown

The Atrium Hotel on Third

3.5 star property
8.4 out of 10, Very good, (717)
"The hotel was quiet, bed was comfortable, and room was clean. There wasn't a lot of options for breakfast and no hot food was offered."
The price is S$153
includes taxes & fees
3 Aug - 4 Aug
The Atrium Hotel on Third

AmericInn by Wyndham Quincy

2.0 star property
7.6 out of 10, Good, (252)
"Great experience "
The price is S$134
includes taxes & fees
15 Aug - 16 Aug
AmericInn by Wyndham Quincy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mississippi River Hotel Reviews

Destinations near

Mark Twain Boyhood Home and Museum
Mark Twain Boyhood Home and Museum

Mark Twain Boyhood Home and Museum

4.5/5(2 reviews)

Find out about the history of Hannibal with a stop at Mark Twain Boyhood Home and Museum. While in this family-friendly area, you can savour the top-notch restaurants.

Mark Twain Memorial Lighthouse
Mark Twain Memorial Lighthouse

Mark Twain Memorial Lighthouse

4/5(1 review)

You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savour the top-notch restaurants.

Jim's Journey: The Huck Finn Freedom Center

Jim's Journey: The Huck Finn Freedom Center

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your holiday in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

Frequently asked questions

What's the area like around Mississippi River?

Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.

What's the best hotel to stay close to Mississippi River?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Clayton Plaza Hotel & Extended Stay and Drury Plaza Hotel St. Louis at the Arch.

If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.