What is Main Street like?

Main Street is a neighbourhood that travellers like for its art, university setting and entertainment choices.

If I need to cancel my hotel reservation in Main Street, will I receive a refund?

Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view top deals in Main Street.

What is there to do around this Ann Arbor neighbourhood?

Ann Arbor Hands On Museum, Ann Arbor Art Center and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.

Top 10 Main Street Hotels of 2025

Top 10 Hotels in Main Street

Two single beds with dark headboards and white bedding, set against a teal accent wall.

"It was a nice stay"

includes taxes & fees

18 Aug - 19 Aug

Two single beds with white linens and wooden headboards, a cityscape painting, and a bedside table with a lamp and phone.

"Clean and friendly as usual"

includes taxes & fees

3 Aug - 4 Aug

Stroll through the serene garden, surrounded by lush greenery and a charming picket fence.

"It was in a nice location"

Two single beds with patterned bedspreads, a framed picture of a bridge, and a nightstand with a lamp and telephone.

" Very clean property. "

includes taxes & fees

18 Aug - 19 Aug

Enjoy a diverse selection of dishes at our buffet, featuring multiple self-service stations with glass covers and metal trays.

"This property was clean, safe and great for a staycation. It was in about five to 12 minutes driving distance to restaurants and shopping. "

includes taxes & fees

3 Aug - 4 Aug

Two single beds with white linens, a desk with flat-screen TV, and a coffee maker.

"The price was decent "

includes taxes & fees

2 Aug - 3 Aug

Welcome to the Red Roof Inn, featuring a flat roof design and beautifully maintained grounds.

"industrial area, good for business visit"

includes taxes & fees

7 Aug - 8 Aug

Relax and work in style at our lobby, featuring a reception desk, comfortable seating area, and large window with a view.

"A delicious breakfast and also very comfy as great area. Lots of walk dining options and CVS too"

includes taxes & fees

11 Aug - 12 Aug

Welcome to our hotel lobby, where a reception desk and artwork adorn the space, complemented by a striped carpet and tiled floor.

"Great for short buisness stays"

includes taxes & fees

8 Aug - 9 Aug

Welcome to our lobby, featuring a polished reception desk, comfortable seating, and a warm, inviting atmosphere.

"We stay here every year for softball, always accommodating! "

includes taxes & fees

7 Aug - 8 Aug

Relax by the pool surrounded by comfortable lounge chairs and a small table.

"Friendly staff great room"

includes taxes & fees

31 Aug - 1 Sept

Welcome to our reception area, where guests can enjoy a selection of snacks and amenities.

"Nice place to stay for the price"

includes taxes & fees

31 Aug - 1 Sept

Welcome to our hotel, where guests can check in at the reception desk, surrounded by a beautiful piece of artwork.

"This property was spot on with the Expedia review. I wish the breakfast was better."

includes taxes & fees

4 Aug - 5 Aug

Restful retreat with a neatly made bed and bedside lamps.

"This property had a decent breakfast and friendly staff. "

includes taxes & fees

26 Aug - 27 Aug

Check in and unwind in our stylish lobby, featuring a reception desk, cozy seating area, and warm fireplace.

"Staff was very friendly, room was mostly clean (except for a few things found under the bed), pool was clean and not over crowded, lots of places to walk to if you want. I would definitely stay here again the next time we are in town. "

includes taxes & fees

3 Aug - 4 Aug

1 bedroom, blackout curtains, free WiFi, bed sheets

"Very great place"

includes taxes & fees

3 Aug - 4 Aug

Relax by the clear, rectangular pool surrounded by lounge chairs and a table.

"Property was clean and people were nice "

includes taxes & fees

7 Aug - 8 Aug

Enjoy a self-service dining experience with a variety of food options available.

"Holiday has a name and they live up to it very nice rooms and stay"

includes taxes & fees

17 Aug - 18 Aug

Two double beds with white linens, flat-screen TV, and striped wallpaper.

"Very clean and although still in the middle of renovations the new rooms were lovely. "

includes taxes & fees

31 Aug - 1 Sept

Relax in the serene outdoor patio area with comfortable wicker chairs and umbrellas.

"Beds were comfortable"

includes taxes & fees

17 Aug - 18 Aug

Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Main Street

Find the best Main Street areas for the activities you enjoy most.

South Central

3 out of top 10 points of interest in this area

If you're spending some time in South Central, Yost Ice Arena and Michigan Stadium are top sights worth seeing.

See properties

Bryant Pattengill East

If you're spending some time in Bryant Pattengill East, Cobblestone Farm and Buhr Park are top sights worth seeing.

See properties

Downtown

If you're spending some time in Downtown, Ann Arbor Hands On Museum and Kempf House Museum are top sights worth seeing.

See properties

University of Michigan which includes a garden

Bryant Pattengill West

2 out of top 10 points of interest in this area

While visiting Bryant Pattengill West, you might make a stop by sights like Briarwood Mall and Lake Forest Golf Club.

See properties

Old West Side

If you're looking for some top things to see and do in Old West Side and surrounding area, you can visit Ann Arbor Hands On Museum and University of Michigan Museum of Art.

See properties