S$453 Cheap Flights from Santiago to Panama City

View S$453 flight on Thu, 11 Sep, 2025Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Tocumen Intl. Airport (PTY)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 40% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Santiago to Panama City (SCL-PTY)

Prices were available within the past 7 days and start at S$453 for one-way flights and S$796 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$796 Return, found 2 days ago
S$796
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$796 found 2 days ago
avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,071 Return, found 2 days ago
S$1,071
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,071 found 2 days ago
Copa
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,415 Return, found 2 days ago
S$1,415
Return
found 2 days ago
Select Copa flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,415 found 2 days ago
Copa
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,434 Return, found 2 days ago
S$1,434
Return
found 2 days ago
Select Copa flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,434 found 2 days ago
Copa
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,661 Return, found 2 days ago
S$1,661
Return
found 2 days ago
Select Copa flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,661 found 2 days ago
avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,782 Return, found 2 days ago
S$1,782
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,782 found 2 days ago
avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,820 Return, found 2 days ago
S$1,820
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,820 found 2 days ago
avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,892 Return, found 2 days ago
S$1,892
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,892 found 2 days ago
avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$1,922 Return, found 2 days ago
S$1,922
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$1,922 found 2 days ago
Delta
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$2,165 Return, found 2 days ago
S$2,165
Return
found 2 days ago
Select Delta flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$2,165 found 2 days ago
Delta
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$3,019 Return, found 2 days ago
S$3,019
Return
found 2 days ago
Select Delta flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$3,019 found 2 days ago
American Airlines
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$3,029 Return, found 2 days ago
S$3,029
Return
found 2 days ago
Select American Airlines flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$3,029 found 2 days ago
avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$3,040 Return, found 2 days ago
S$3,040
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$3,040 found 2 days ago
avianca
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$3,111 Return, found 2 days ago
S$3,111
Return
found 2 days ago
Select avianca flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$3,111 found 2 days ago
Delta
Thu, 11 Sep - Mon, 15 Sep
SCL
Santiago
PTY
Panama City
S$3,128 Return, found 2 days ago
S$3,128
Return
found 2 days ago
Select Delta flight, departing Thu, 11 Sep from Santiago to Panama City, returning Mon, 15 Sep, priced at S$3,128 found 2 days ago

Find the cheapest month to fly from Santiago (SCL) to Panama City (PTY)

November is typically the cheapest month to fly

From S$462 - S$981 per traveller.

Graph displaying average flight prices per month

Santiago to Panama City route information
Origin airport
Arturo Merino Benitez
Destination airport
Tocumen Intl.
Return price
S$796
Distance
4780 km
Average flight time
5 hours 51 mins

Perfect flights from Santiago to Panama City

Your Journey from Santiago to Panama City

Start your unforgettable journey with Expedia. Our broad selection of flights from Santiago to Panama City caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including avianca, Copa, Delta, American Airlines. Our selection of flights from Arturo Merino Benitez to Tocumen Intl. caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with Santiago to Panama City Flights

Experience the joy of finding cheap flights from Arturo Merino Benitez to Tocumen Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$453 and roundtrip prices from S$796*.
 

Pre-Flight Essentials

Ensure a smooth journey from Santiago to Panama City with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Panama City

Picture yourself stepping off the plane in Panama City and immersing yourself in the unique atmosphere of Tocumen. From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your Santiago to Panama City Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from Santiago to Panama City.
 

Beyond the Flight – Exploring Panama City

With Expedia, your adventure extends beyond the flight. Explore Panama City at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from Santiago to Panama City with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from Santiago to Panama City with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from Santiago International Airport to Tocumen Intl. Airport (PTY)?
Start packing your bags, because round-trip journeys from Santiago International Airport to Panama Airport start from S$796. That's based on fares advertised within the last 7 days on Expedia for flights departing within the next year. Prices can rise quickly, so book now to get the best deal. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from SCL to Panama Airport?
Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the instructions on our Customer Service Portal.
How do I find cheap flights from Nuevo Pudahuel Airport to Tocumen Intl. Airport (PTY) that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for SCL to PTY flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Santiago International Airport to PTY?
The distance is around 4,800 kilometres. Earplugs? Check. Toothbrush? Check. You'll need to pack all the essentials for this long-haul Santiago to Tocumen flight.
Which airlines fly direct from Santiago International Airport to Panama Airport?
Flying directly from Nuevo Pudahuel Airport to Panama Airport is a cinch with Copa Airlines (CM). This top airline offers 169 flights each month.
Are SCL to Panama Airport flight tickets cheaper when they're purchased at the last minute?
Last-minute bookings from Santiago International Airport to PTY can be hit-or-miss. You may be able to find a bargain, but you could also miss out completely! If you'd prefer to start planning ahead of time, Expedia compares flight deals up to 12 months in advance. Just keep in mind that not all airlines release their prices that far in advance. Our advice? Check back often as prices are updated frequently.

Explore a world of travel with Expedia

*Available to Expedia members.