There are several airlines that operate frequent flights from Miami (MIA) to Panama (PTY) including

• American Airlines with 168 flights a week
• United Airlines with 45 flights a week
• COPA Airlines with 42 flights a week
• LATAM Airlines Group with 17 flights a week
• Aeromexico with 2 flights a week

The earliest flight leaves Miami Intl. Airport at 04:59 and arrives at Tocumen Intl. Airport at 08:01. The last flight of the day departs Miami at 18:17 and arrives at Panama at 21:27.

The flight distance from Miami to Panama is about 1871 km, the shortest flight is 03 hours 01 minutes with United Airlines.

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