There are several airlines that operate frequent flights from Melbourne (MEL) to Frankfurt (FRA) including

• Qantas Airways with 50 flights a week
• Emirates with 38 flights a week
• Virgin Australia with 26 flights a week
• PIA with 17 flights a week
• Air Berlin with 17 flights a week

The earliest flight leaves Tullamarine Airport at 00:50 and arrives at Frankfurt Intl. Airport at 05:10. The last flight of the day departs Melbourne at 23:55 and arrives at Frankfurt at 19:25.

The flight distance from Melbourne to Frankfurt is about 16596 km, the shortest flight is 21 hours 40 minutes with Virgin Australia.

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