There are several airlines that operate frequent flights from Madrid (MAD) to Athens (ATH) including

• IBERIA with 102 flights a week
• Air Europa with 87 flights a week
• Air Berlin with 36 flights a week
• Lufthansa Cargo with 35 flights a week
• Alitalia with 26 flights a week

The earliest flight leaves Adolfo Suarez Madrid Barajas Airport at 01:30 and arrives at Eleftherios Venizelos Airport at 03:55. The last flight of the day departs Madrid at 23:20 and arrives at Athens at 22:40.

The flight distance from Madrid to Athens is about 2389 km, the shortest flight is 03 hours 30 minutes with Vueling Airlines."

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