There are several airlines that operate frequent flights from Lisbon (LIS) to Madrid (MAD) including

• TAP Portugal with 129 flights a week
• IBERIA with 30 flights a week
• Air Europa with 26 flights a week
• with 11 flights a week
• United Airlines with 3 flights a week

The earliest flight leaves Portela Airport at 06:45 and arrives at Adolfo Suarez Madrid Barajas Airport at 09:00. The last flight of the day departs Lisbon at 21:35 and arrives at Madrid at 23:50.

The flight distance from Lisbon to Madrid is about 515 km, the shortest flight is 01 hours 10 minutes with Air Europa.

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