There are several airlines that operate frequent flights from Las Vegas (LAS) to Chicago (ORD) including

• American Airlines with 198 flights a week
• Delta Air Lines with 152 flights a week
• United Airlines with 72 flights a week
• with 47 flights a week
• with 16 flights a week

The earliest flight leaves McCarran Intl. Airport at 00:08 and arrives at O'Hare Intl. Airport at 00:15. The last flight of the day departs Las Vegas at 23:59 and arrives at Chicago at 23:59.

The flight distance from Las Vegas to Chicago is about 2444 km, the shortest flight is 03 hours 26 minutes with .

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