There are several airlines that operate frequent flights from Rome (FCO) to Cairo (CAI) including

• Alitalia with 56 flights a week
• Turkish Airlines with 20 flights a week
• MEA with 17 flights a week
• Egyptair with 16 flights a week
• Aegean Airlines with 7 flights a week

The earliest flight leaves Fiumicino Leonardo da Vinci Intl. Airport at 11:55 and arrives at Cairo Intl. Airport at 01:35. The last flight of the day departs Rome at 22:25 and arrives at Cairo at 21:35.

The flight distance from Rome to Cairo is about 2161 km, the shortest flight is 03 hours 10 minutes with Tunisair.

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