There are several airlines that operate frequent flights from Denver (DEN) to Frankfurt (FRA) including

• United Airlines with 236 flights a week
• American Airlines with 92 flights a week
• Delta Air Lines with 80 flights a week
• Lufthansa Cargo with 50 flights a week
• Air Canada with 45 flights a week

The earliest flight leaves Denver Intl. Airport at 17:25 and arrives at Frankfurt Intl. Airport at 11:00. The last flight of the day departs Denver at 18:35 and arrives at Frankfurt at 12:00.

The flight distance from Denver to Frankfurt is about 8132 km, the shortest flight is 09 hours 35 minutes with United Airlines."

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