S$250 Cheap Flights from Des Moines to Panama City

View S$250 flight on Mon, 1 Sep, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Des Moines to Panama City (DSM-PTY)

Prices were available within the past 7 days and start at S$250 for one-way flights and S$582 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$582 Return, found 6 days ago
S$582
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$582 found 6 days ago
Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$626 Return, found 6 days ago
S$626
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$626 found 6 days ago
Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$652 Return, found 6 days ago
S$652
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$652 found 6 days ago
American Airlines
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$688 Return, found 6 days ago
S$688
Return
found 6 days ago
Select American Airlines flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$688 found 6 days ago
Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$694 Return, found 6 days ago
S$694
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$694 found 6 days ago
American Airlines
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$695 Return, found 6 days ago
S$695
Return
found 6 days ago
Select American Airlines flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$695 found 6 days ago
Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$696 Return, found 6 days ago
S$696
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$696 found 6 days ago
Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$701 Return, found 6 days ago
S$701
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$701 found 6 days ago
American Airlines
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$702 Return, found 6 days ago
S$702
Return
found 6 days ago
Select American Airlines flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$702 found 6 days ago
Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$708 Return, found 6 days ago
S$708
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$708 found 6 days ago
Delta
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$715 Return, found 6 days ago
S$715
Return
found 6 days ago
Select Delta flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$715 found 6 days ago
United
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$723 Return, found 6 days ago
S$723
Return
found 6 days ago
Select United flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$723 found 6 days ago
American Airlines
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$723 Return, found 6 days ago
S$723
Return
found 6 days ago
Select American Airlines flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$723 found 6 days ago
American Airlines
Mon, 1 Sep - Mon, 8 Sep
DSM
Des Moines
PTY
Panama City
S$742 Return, found 6 days ago
S$742
Return
found 6 days ago
Select American Airlines flight, departing Mon, 1 Sep from Des Moines to Panama City, returning Mon, 8 Sep, priced at S$742 found 6 days ago

Find the cheapest month to fly from Des Moines (DSM) to Panama City (PTY)

August is typically the cheapest month to fly

From S$414 - S$751 per traveller.

Graph displaying average flight prices per month

Des Moines to Panama City route information
Origin airport
Des Moines Intl.
Destination airport
Tocumen Intl.
Return price
S$581
Distance
3849 km

Perfect flights from Des Moines to Panama City

Your Journey from Des Moines to Panama City

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*Note: Prices may vary based on availability and are subject to change.

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