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Top Luxury Hotels in Syracuse

Beautiful view of the beach with palm trees

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Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Syracuse?
Travel to Catania (CTA-Fontanarossa) Airport or Comiso (CIY-Vincenzo Magliocco) Airport, and then treat yourself to a stay at one of 6 Syracuse luxury hotels. While you’re visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best luxury place to stay in Syracuse?
Grand Hotel Ortigia Siracusa is a luxury hotel with a private beach and spa services, and it’s a popular choice for Expedia travellers looking for an elegant place to stay. Wellness & Spa Hotel Principe di Fitalia and Minareto are other upscale choices for your trip.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia’s 6 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you’re splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It’s easier to get around town in style when you know your options. To venture out into the surrounding area, ride one of the trains from Syracuse Station or Targia Station.