Find Southern Illinois Spa Hotels from S$151

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Hotels with Spa

Tonight
31 Jul - 1 Aug
Tomorrow
1 Aug - 2 Aug
This weekend
1 Aug - 3 Aug
Next weekend
8 Aug - 10 Aug

Top Hotels with Spa in Southern Illinois

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"Great place to stay. "
The price is S$151
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Walker's Bluff Casino Resort
Indoor pool, seasonal outdoor pool

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (360)
"I would love to stay here again, shoutout to their beds!! "
Walker's Bluff Casino Resort
1895 Washington Hotel
Property entrance

1895 Washington Hotel

3.0 star property
9.0 out of 10, Wonderful, (368)
"Area was walkable and we were able to sit on the porch and enjoy some beers."
1895 Washington Hotel
21C Museum Hotel St Louis
Exterior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1280)
"Great place to stay. "
The price is S$237
includes taxes & fees
31 Aug - 1 Sept
21C Museum Hotel St Louis
Ameristar Casino Resort and Spa
6 restaurants, breakfast served

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1003)
"NICE AREA TO STAY"
The price is S$278
includes taxes & fees
10 Aug - 11 Aug
Ameristar Casino Resort and Spa
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1001)
"Great hotel, loved the room"
The price is S$640
includes taxes & fees
11 Aug - 12 Aug
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (540)
"Wish they still had a pool"
The price is S$874
includes taxes & fees
2 Aug - 3 Aug
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"The staff was helpful and friendly. Room was clean "
SARAH 4-night trip
Posted 2 days ago
Drury Plaza Hotel Mt. Vernon