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Check Santa Maria hotel prices

Tonight
21 Nov - 22 Nov
Tomorrow night
22 Nov - 23 Nov
This weekend
22 Nov - 24 Nov
Next weekend
29 Nov - 1 Dec

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Top 10 trending Santa Maria hotels

Casa Amancay
Property entrance
Casa Amancay
2.5 star property
8.0 out of 10, Very good, (7)
"Ni siquiera nos recibieron, no reconocieron la reserva hecha por esta pagina. No había ni quien nos atienda, lo llame al dueño y por teléfono , nos dijo que no reconocía la reserva de esta pagina, que no tenia lugar y que era mi problema no suyo. "
Casa Amancay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
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Frequently asked questions

If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Maria.

What's it like to stay in Santa Maria?

Visitors can enjoy all that Santa Maria has to offer, including its wineries. This city also attracts tourists with its relaxing and scenic setting. There are 2 hotels and other accommodation options in the surrounding area. Find out more about Santa Maria.

What is there to see in Santa Maria?

Places to visit in the wider area include Quilmes Ruins and Pachamama Museum. Take a look at what more there is to see and do in Expedia's Santa Maria guide.

What's the weather like in Santa Maria?

The hottest months are usually January and December, with an average temperature of 23°C, while the coldest months are July and June, with an average of 13°C. The rainiest months in Santa Maria are January, February, December and March, with each month seeing an average of 179 mm of rainfall.