San Francisco

Panama City

Photo by Hideki Yamagata
Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Nóra Széll
Photo by Panama Roadrunner
Photo by Panama Roadrunner

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

4.5/5(8 reviews)

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall

ATLAPA Conventions Center

Learn about the events happening in ATLAPA Conventions Center during your trip to Panama City. Stroll along the seaside in this vibrant area or visit its lively bars.

ATLAPA Conventions Center

Multicentro Panama

4/5(1 review)

During your trip to Panama City, you can find the perfect gifts to bring home at Multicentro Panama. Stroll along the seaside or visit the casinos in this vibrant area.

Multicentro Panama

Pacific Center

You can browse for the perfect souvenirs at Pacific Center during your visit to Panama City. You can enjoy the restaurants while in the area.

Pacific Center

Hospital Punta Pacífica

If Hospital Punta Pacífica is what brings you to town, hopefully you'll have a chance to explore more of Panama City.

Hospital Punta Pacífica

Panama Canal Murals

4/5(1 review)

You can learn about the history of Panama City with a stop at Panama Canal Murals. Stroll along the seaside in this vibrant area or visit its top-notch restaurants.

Panama Canal Murals

Things to do

Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

S$199
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
The Cathedral Basilica of Santa María La Antigua stands as a monumental beacon of faith, the first of its kind in America. Consecrated in 1796, its foundations were laid in 1688, marking over a centur

HALF-DAY City and Panama Canal Tour: Shared or Private

S$111
per adult
100% of travellers recommend
HALF-DAY City and Panama Canal Tour: Shared or Private
La casa de papel Day tour in San Blas Islands - All inclusive- No hidden fees.

All included - Day tour in San Blas Islands - No extra fees

S$145
per adult
All included - Day tour in San Blas Islands - No extra fees
Boat Tour to Monkey Island in the Panama Canal

Boat tour in the Panama Canal to Monkeys and sloths islands

S$99
per adult
92% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
Full-Day SAN BLAS ISLAND & Snorkeling Tour + Transport from Panama City

Full-Day SAN BLAS ISLAND Tour + Transport from Panama City

S$191
per adult
Full-Day SAN BLAS ISLAND Tour + Transport from Panama City
Live the Experience of a Full Day in San Blas

Live the Experience of a Full Day in San Blas

S$222
per adult
100% of travellers recommend
Live the Experience of a Full Day in San Blas
See all activities in Panama City

Top hotels in San Francisco

JW Marriott Panama
JW Marriott Panama
5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is S$264 per night from 2 May to 3 May
S$264
includes taxes & fees
2 May - 3 May
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,001 reviews)
"Everything about it was spectacular. Food was wonderful. Casino next door. Pool is fun. And the staff are pleasant."

Reviewed on 13 Apr, 2025

JW Marriott Panama
Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is S$195 per night from 2 May to 3 May
S$195
includes taxes & fees
2 May - 3 May
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (861 reviews)
5 Stars all the way
"This was simply put, an outstanding stay from start to finish. The staff were amazing, the room was clean, the housekeeping was always on time and helpful, just a wonderful experience for me and my 3 kids. We were on the club floor which was an extra special experience. These folks know what they ..."

Reviewed on 6 Apr, 2025

Sheraton Grand Panama
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
The price is S$169 per night from 28 Apr to 29 Apr
S$169
includes taxes & fees
28 Apr - 29 Apr
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,011 reviews)
"Pleasant hotel with a good breakfast buffet each morning. Also offered dinner buffets on some nights for a reasonable rate. Pool was great, just hard to get a towel in the evening. Nice staff and great view of the city from bayside rooms. Some noise from the nearby road and very limited restaurant ..."

Reviewed on 20 Apr, 2025

Plaza Paitilla Inn Hotel
Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
The price is S$162 per night from 3 May to 4 May
S$162
includes taxes & fees
3 May - 4 May
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,005 reviews)
"One of the best hotels I have stayed"

Reviewed on 18 Apr, 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
The price is S$183 per night from 25 Apr to 26 Apr
S$183
includes taxes & fees
25 Apr - 26 Apr
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (859 reviews)
"The furniture was a little dated but the hotel was awesome. I will return"

Reviewed on 21 Apr, 2025

Megapolis Hotel Panamá
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is S$135 per night from 26 Apr to 27 Apr
S$135
includes taxes & fees
26 Apr - 27 Apr
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,146 reviews)
"Excelente"

Reviewed on 17 Apr, 2025

Decapolis Hotel Panama City
See all 1,415 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Bingo 90 while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
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Pueblo Nuevo

While there might not be top attractions in Pueblo Nuevo, you can explore the larger area and discover places like El Dorado Mall and Multiplaza Pacific Mall.

Pueblo Nuevo
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El Cangrejo

4/5(5 area reviews)

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

El Cangrejo

San Francisco