Photo by Amber Palmer

Hotels near Mayo Clinic Florida

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Jun - 30 Jun
Tomorrow
30 Jun - 1 Jul
Next weekend
4 Jul - 6 Jul
In two weeks
11 Jul - 13 Jul

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels Near Mayo Clinic Florida

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Reception

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (398)
"The place was clean and staff was wonderful. Will be staying again!"
The price is S$253
includes taxes & fees
4 Jul - 5 Jul
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
TownePlace Suites by Marriott Jacksonville East
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

3.0 star property
9.2 out of 10, Wonderful, (464)
"Nice and quiet hotel "
The price is S$175
includes taxes & fees
14 Jul - 15 Jul
TownePlace Suites by Marriott Jacksonville East
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Terrace/patio

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1002)
"I loved our stay"
The price is S$172
includes taxes & fees
27 Jul - 28 Jul
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
8.4 out of 10, Very good, (724)
"Everything "
The price is S$233
includes taxes & fees
19 Jul - 20 Jul
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Exterior

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
8.4 out of 10, Very good, (1008)
"Great hotel"
The price is S$188
includes taxes & fees
13 Jul - 14 Jul
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Element Jacksonville Beach
Lobby

Element Jacksonville Beach

3.0 star property
9.8 out of 10, Exceptional, (478)
"I would book this hotel again if im in town again.."
The price is S$209
includes taxes & fees
6 Jul - 7 Jul
Element Jacksonville Beach
Salt Air Inn & Suites
BBQ/picnic Area

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (336)
"Great place to stay"
The price is S$256
includes taxes & fees
30 Jun - 1 Jul
Salt Air Inn & Suites
The Hotel Palms
1 bedroom, down duvets, minibar, iron/ironing board

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (287)
"Easy comfy convenient. "
The price is S$288
includes taxes & fees
1 Jul - 2 Jul
The Hotel Palms
Ponte Vedra Inn & Club
Reception

Ponte Vedra Inn & Club

5.0 star property
9.4 out of 10, Exceptional, (798)
"We enjoyed our stay Friendly Professional Staff "
The price is S$605
includes taxes & fees
30 Jun - 1 Jul
Ponte Vedra Inn & Club
The Lodge and Club at Ponte Vedra Beach
Beach/ocean view

The Lodge and Club at Ponte Vedra Beach

5.0 star property
9.4 out of 10, Exceptional, (669)
"Loved our stay, my sixth at this property. JR the waiter at breakfast at the Inn, was delightful!Cant wait to come back!"
The price is S$889
includes taxes & fees
30 Jun - 1 Jul
The Lodge and Club at Ponte Vedra Beach
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"Great service, quality, and food!"
The price is S$190
includes taxes & fees
1 Jul - 2 Jul
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
AC Hotel Jacksonville St Johns Town Center
Lounge

AC Hotel Jacksonville St Johns Town Center

2.5 star property
9.4 out of 10, Exceptional, (113)
"Great place to stay, easy in/out, nice facilities and plenty to do in the area. "
The price is S$209
includes taxes & fees
1 Jul - 2 Jul
AC Hotel Jacksonville St Johns Town Center
Holiday Inn Express Jacksonville Beach by IHG
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

2.5 star property
9.2 out of 10, Wonderful, (1001)
"Clean convenient and close to dining "
The price is S$201
includes taxes & fees
30 Jun - 1 Jul
Holiday Inn Express Jacksonville Beach by IHG
Four Points by Sheraton Jacksonville Beachfront
Exterior

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
9.2 out of 10, Wonderful, (1002)
"Beach access...parking and the staff was amazing"
The price is S$294
includes taxes & fees
6 Jul - 7 Jul
Four Points by Sheraton Jacksonville Beachfront
Hampton Inn Jacksonville Beach/Oceanfront
2 outdoor pools, pool umbrellas, pool loungers

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
9.2 out of 10, Wonderful, (2282)
"Very nice hotel. "
The price is S$254
includes taxes & fees
6 Jul - 7 Jul
Hampton Inn Jacksonville Beach/Oceanfront
Hyatt Place Jacksonville / St. Johns Town Center
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

3.0 star property
9.2 out of 10, Wonderful, (1002)
"Very happy with our stay."
The price is S$155
includes taxes & fees
20 Jul - 21 Jul
Hyatt Place Jacksonville / St. Johns Town Center
Sheraton Jacksonville Hotel
Property amenity

Sheraton Jacksonville Hotel

4.0 star property
9.2 out of 10, Wonderful, (1002)
"Very friendly staff and property is nice and well maintained. Close to mall and nice food options"
The price is S$168
includes taxes & fees
3 Jul - 4 Jul
Sheraton Jacksonville Hotel
Best Western Oceanfront
On the beach

Best Western Oceanfront

2.5 star property
9.0 out of 10, Wonderful, (1006)
"Great location "
The price is S$217
includes taxes & fees
22 Jul - 23 Jul
Best Western Oceanfront
Springhill Suites By Marriott Jacksonville Beach Oceanfront
On the beach, windsurfing

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
9.0 out of 10, Wonderful, (510)
"The rooms were very clean and comfortable. The location was excellent. "
The price is S$269
includes taxes & fees
6 Jul - 7 Jul
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Margaritaville Jacksonville Beach
On the beach, white sand, surfing, kayaking

Margaritaville Jacksonville Beach

2.5 star property
9.0 out of 10, Wonderful, (2943)
"Location and staff was excellent "
Margaritaville Jacksonville Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 34 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels are there near Mayo Clinic Florida?

Expedia has 34 hotels and other accommodation options within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Wilson Center For the Arts and Players by the Sea. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Gonzales Park. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.