Photo by Amber Palmer

Hotels near Mayo Clinic Florida

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels Near Mayo Clinic Florida

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (349)
"This hotel has many patients that go to Mayo Clinic stay. There is not adequate. Handicap parking. I stay there often and almost always need to park on the side of the building and walk. Also the room service is a nice addition. A suggestion would be to have a direct line to call the restaurant to place orders, currently you need to call the front desk. "
The price is S$278
includes taxes & fees
22 Mar - 23 Mar
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

TownePlace Suites by Marriott Jacksonville East

2.5 star property
9.2 out of 10, Wonderful, (422)
"I love the room and kitchen, I wish I could live there.😀 The staffs are great! "
The price is S$197
includes taxes & fees
30 Mar - 31 Mar
TownePlace Suites by Marriott Jacksonville East

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1000)
"Affordable option very close to Mayo."
The price is S$204
includes taxes & fees
17 Mar - 18 Mar
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
8.4 out of 10, Very good, (699)
"This property is perfect for anyone needing to visit the Mayo Clinic in Jacksonville, Florida. It is convinient and has a shuttle every 15 minutes to every spot in the Mayo Campus. All the employees were helpful and availble. We enjoyed our stay there."
The price is S$243
includes taxes & fees
22 Mar - 23 Mar
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
8.4 out of 10, Very good, (1001)
"Awesome "
The price is S$203
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (298)
"The proprietors were welcoming and generous. Room was great. Thanks for a trouble free stay!"
The price is S$256
includes taxes & fees
19 Mar - 20 Mar
Salt Air Inn & Suites

Element Jacksonville Beach

3.0 star property
9.6 out of 10, Exceptional, (453)
"The staff were friendly and helpful. The breakfast was great. It's a quick walk to the beach, a ton of food options nearby, and very convenient to the Mayo clinic. We will definitely stay again. "
The price is S$204
includes taxes & fees
23 Mar - 24 Mar
Element Jacksonville Beach

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
9.6 out of 10, Exceptional, (1015)
"Nice property and close to plenty of dining options. "
The price is S$204
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (281)
"Relaxing and calm "
The price is S$325
includes taxes & fees
19 Mar - 20 Mar
The Hotel Palms

AC Hotel Jacksonville St Johns Town Center

2.5 star property
9.6 out of 10, Exceptional, (82)
"Very impressed with the hotel. This will be our go to for future stops in Jacksonville!"
The price is S$286
includes taxes & fees
30 Mar - 31 Mar
AC Hotel Jacksonville St Johns Town Center

Ponte Vedra Inn & Club

5.0 star property
9.4 out of 10, Exceptional, (779)
"Property under significant construction. Many restaurants and facilities not available requiring transport to sister property. Expedia and the Inn failed to advise visitors of significant property issues on the websites. Shame on you both. While I have complained of these misrepresentations no adjustments were made to my booking and THE WEBSITES REMAIN UNCORRECTED AND MISLEADING in my opinion."
The price is S$631
includes taxes & fees
23 Mar - 24 Mar
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

5.0 star property
9.4 out of 10, Exceptional, (656)
"10 very clean and family friendly"
The price is S$779
includes taxes & fees
30 Mar - 31 Mar
The Lodge and Club at Ponte Vedra Beach

Holiday Inn Express Jacksonville Beach by IHG

2.5 star property
9.2 out of 10, Wonderful, (1000)
"Polite helpful staff, very clean and nice rooms"
The price is S$198
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express Jacksonville Beach by IHG

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
9.2 out of 10, Wonderful, (2067)
"The place was nice & clean. The ability to use the app for my room key was amazing. To check in & out through the app was convenient for I arrived late upon arrival. "
The price is S$235
includes taxes & fees
23 Mar - 24 Mar
Hampton Inn Jacksonville Beach/Oceanfront

Seahorse Oceanfront Inn

2.5 star property
9.2 out of 10, Wonderful, (403)
"Great property for a relaxing few days at the beach. The surrounding area is excellent for restaurants and shopping. Very nice room and great service. Would recommend to anyone."
The price is S$252
includes taxes & fees
7 Apr - 8 Apr
Seahorse Oceanfront Inn

Hyatt Place Jacksonville / St. Johns Town Center

3.0 star property
9.2 out of 10, Wonderful, (1021)
"Loved everything from the back patio to the breakfast! Everything was wonderful "
The price is S$163
includes taxes & fees
23 Mar - 24 Mar
Hyatt Place Jacksonville / St. Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center

2.5 star property
9.2 out of 10, Wonderful, (688)
"Tru by hilton in jax town center was great! I only stayed for a night, and didn’t have to go to the desk when I got in late. Only one star dinged in cleanliness cuz I found hairs in the bed and bathroom which I wasn’t a fan of. Overall very clean otherwise and a good experience!"
The price is S$215
includes taxes & fees
10 Apr - 11 Apr
Tru By Hilton Jacksonville St Johns Town Center

Sheraton Jacksonville Hotel

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Very nice property in a nice area. Very clean "
The price is S$223
includes taxes & fees
27 Mar - 28 Mar
Sheraton Jacksonville Hotel

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
9.0 out of 10, Wonderful, (426)
"It was off season so very quiet. "
The price is S$304
includes taxes & fees
23 Mar - 24 Mar
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Margaritaville Jacksonville Beach

2.5 star property
9.0 out of 10, Wonderful, (2873)
"My overall experience at the property was amazing…! "
The price is S$309
includes taxes & fees
17 Mar - 18 Mar
Margaritaville Jacksonville Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Mayo Clinic Florida
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 34 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels are there near Mayo Clinic Florida?

Expedia has 34 hotels and other accommodation options within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.