Find Defne Spa Hotels

  • Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Top Hotels with Spa in Defne

Zeyn Hotel

8.8 out of 10, Excellent, (68)
"Great clean friendly staff excellent food and service. "
Zeyn Hotel

Tarbus Hotel

3.0 star property
7.0 out of 10, Good, (8)
"."
Tarbus Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Defne
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Looking to holiday at a spa hotel in Defne?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Spa hotels are the perfect way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in Defne?
Tarbus Hotel is a top spa hotel featuring a fitness centre, a bar, an outdoor pool and a restaurant. Enjoy a body scrub, Thai massage or body wrap at the on-site spa.
How many spa hotels are there in Defne?
Among Expedia’s 11 accommodation options in Defne, there is 1 spa hotel.
What's there to see and do in Defne?
Experience Defne and visit Harbiye Waterfall, Monastery of St. Simeon and Vakifli Village. If you have extra time while you’re in the area, you might want to stop by Antakya Archaelogical Museum and Necmi Asfuroğlu Archaeology Museum.
What is a Defne spa hotel?
Spa hotels in Defne provide lodging and have an on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.