La Mesa Car Rental

Search and Compare from Car Companies in La Mesa

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

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Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Can I rent a car from Tocumen Intl. Airport (PTY)?
Thrifty Car Rental and Sixt are within a quick commute of Tocumen Intl. Airport (PTY). After touching down, it won’t be long before you’re on the road.
What happens if I need to cancel my La Mesa car reservation?
Canceling a booking at least six hours before pickup should allow for a complete refund. But this is not always a given. It’s worth checking your booking confirmation and cancellation policy. Still need help? Hop on our Customer Service Portal.
Why should I rent a La Mesa car with Expedia?
There are tons of reasons to book your next set of wheels with Expedia. We have suppliers to take your pick of in La Mesa, and we’ll make sure you score the best price with our exclusive offers and member prices. Want even bigger savings? Combine your car, flights and hotels into a vacation package. The more you travel and book with Expedia, the bigger the benefits!
How do I find the best car rental deals in La Mesa with Expedia?
Pick up an awesome deal with Expedia. Just choose your preferred car type, select your dates and preferred pickup and drop-off locations, and compare offers from leading rental providers. Save even more when you combine your La Mesa car rental with hotel or flight bookings.
What do you need to rent a car in La Mesa?
You’ll need to present your driver’s license and a credit card when you get to the rental counter. Prior to the pickup date, check with your rental provider whether other documentation is needed. For example, you may also need to provide proof of auto insurance.
Can I rent a car for a month or longer in La Mesa?
You can rent a vehicle for a month or longer in La Mesa, so don’t hestitate to extend that vacation! Just enter your trip dates into our long-term car rental deals page and reserve your ideal ride.
Where can I find a La Mesa car rental if I am younger than 25?
Whether you can rent a vehicle if you are under 25 in La Mesa often depends on the rental company you select. Some places apply a surcharge for young customers aged between 21 and 24 years, however others may not have any additional fees for this age bracket. It’d be wise to read the terms and conditions of your prospective car rental dealer to escape excessive charges when picking up your keys.