Panama Car Rentals

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

Members save 10% more on select hotels, cars, activities and holiday rentals. Sign up.Opens in a new window

Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

Top destinations to rent a car in Panama

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Expedia.com.sg offers car hire in Panama to meet every traveller's needs. Whether you are looking for cheap cars or cars fit for the stars - Expedia.com.sg has the car hire for you. So choose from car hire in Panama or destinations around the world and discover how easy it is to make your car hire on Expedia.com.sg.

Frequently asked questions

What happens if I need to cancel my Panama car reservation?
When you cancel at least six hours in advance of pickup, most prepaid rentals qualify for a refund. However, not every one is eligible for this, so it’s important to familiarize yourself with the policy. Read through your confirmation for the details or visit our Customer Service Portal for more information.
What types of cars can I rent in Panama?
Small in size but big on perks, economy cars are the first choice for many in Panama. They’re easy to handle and park, which is handy if you’ll be doing mostly city driving. And with fantastic fuel-efficiency, these affordable wheels will have you cruising around on the cheap. Want a larger car? Check out our standard, full-size or premium vehicles.
How do I find the best car rental deals in Panama with Expedia?
It’s easy to track down an awesome deal with Expedia. All you have to do is choose your wheels, select your dates and pickup and drop-off points, and compare offers from all the trusted rental providers. Save even more when you bundle your Panama car rental with hotel or flight bookings.
What do you need to rent a car in Panama?
The main requirements are your driver’s license and a credit card in your name. Car rental companies will offer you insurance, which is optional. But you may be asked to provide proof of other coverage if you prefer to opt out. Make sure you check with your supplier to avoid any hassles.
Can I rent a car for a month or longer in Panama?
Yes, and you’re sure to find your ideal set of wheels among our long-term car rental deals. Just enter your trip dates and we’ll show you terrific offers from various leading suppliers.
Where can I find a Panama car rental if I am younger than 25?
The ability to rent a vehicle if you are under 25 years old in Panama often depends on the rental company you choose. Some places have a surcharge for young customers between 21 and 24 years of age, yet others may not have any extra fees for this age bracket. Make sure you go through the terms and conditions of your prospective car rental dealer to escape extra charges when picking up your keys.