There are several airlines that operate frequent flights from Tel Aviv (TLV) to Madrid (MAD) including

• EL AL Israel Airlines with 118 flights a week
• Turkish Airlines with 33 flights a week
• Alitalia with 29 flights a week
• IBERIA with 28 flights a week
• Lufthansa Cargo with 26 flights a week

The earliest flight leaves Ben Gurion Airport at 03:30 and arrives at Adolfo Suarez Madrid Barajas Airport at 08:15. The last flight of the day departs Tel Aviv at 18:45 and arrives at Madrid at 22:15.

The flight distance from Tel Aviv to Madrid is about 3562 km, the shortest flight is 05 hours 05 minutes with Vueling Airlines.

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