S$244 Cheap Flights from San Francisco to Knoxville

View S$244 flight on Sun, 12 Oct, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to McGhee Tyson Airport (TYS)

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Cheap Flights from San Francisco to Knoxville (SFO-TYS)

Prices were available within the past 7 days and start at S$244 for one-way flights and S$500 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$500 Return, found 1 day ago
S$500
Return
found 1 day ago
Select United flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$500 found 1 day ago
United
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$545 Return, found 1 day ago
S$545
Return
found 1 day ago
Select United flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$545 found 1 day ago
United
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$564 Return, found 1 day ago
S$564
Return
found 1 day ago
Select United flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$564 found 1 day ago
United
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$595 Return, found 1 day ago
S$595
Return
found 1 day ago
Select United flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$595 found 1 day ago
United
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$609 Return, found 1 day ago
S$609
Return
found 1 day ago
Select United flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$609 found 1 day ago
American Airlines
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$620 Return, found 1 day ago
S$620
Return
found 1 day ago
Select American Airlines flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$620 found 1 day ago
American Airlines
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$623 Return, found 1 day ago
S$623
Return
found 1 day ago
Select American Airlines flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$623 found 1 day ago
United
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$634 Return, found 1 day ago
S$634
Return
found 1 day ago
Select United flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$634 found 1 day ago
Alaska Airlines
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$759 Return, found 1 day ago
S$759
Return
found 1 day ago
Select Alaska Airlines flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$759 found 1 day ago
Delta
Sat, 11 Oct - Sat, 18 Oct
SFO
San Francisco
TYS
Knoxville
S$801 Return, found 1 day ago
S$801
Return
found 1 day ago
Select Delta flight, departing Sat, 11 Oct from San Francisco to Knoxville, returning Sat, 18 Oct, priced at S$801 found 1 day ago

Find the cheapest month to fly from San Francisco (SFO) to Knoxville (TYS)

January is typically the cheapest month to fly

From S$203 - S$692 per traveller.

Graph displaying average flight prices per month

San Francisco to Knoxville route information
Origin airport
San Francisco Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, United
Return price
S$500
Distance
3385 km

Perfect flights from San Francisco to Knoxville

Your Journey from San Francisco to Knoxville

Start your unforgettable journey with Expedia. Our broad selection of flights from San Francisco to Knoxville caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including Delta, United, American Airlines, Alaska Airlines. Our selection of flights from San Francisco Intl. to McGhee Tyson caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with San Francisco to Knoxville Flights

Experience the joy of finding cheap flights from San Francisco Intl. to McGhee Tyson that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$244 and roundtrip prices from S$500*.
 

Pre-Flight Essentials

Ensure a smooth journey from San Francisco to Knoxville with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Knoxville

Picture yourself stepping off the plane in Knoxville and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your San Francisco to Knoxville Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from San Francisco to Knoxville.
 

Beyond the Flight – Exploring Knoxville

With Expedia, your adventure extends beyond the flight. Explore Knoxville at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from San Francisco to Knoxville with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from San Francisco to Knoxville with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from SFO to McGhee Tyson Airport (TYS)?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip journey from San Francisco Airport to McGhee Tyson Airport (TYS) was S$500. Fares this good don't wait forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Knoxville Airport?
Most flights can be cancelled online, but whether or not you incur a fee differs between airlines. If you do need to cancel your trip, follow the instructions in the Customer Service Portal.
How do I find cheap flights from SFO to Knoxville Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for SFO to TYS flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to McGhee Tyson Airport (TYS)?
The flight distance from San Francisco to Alcoa is 3,400 kilometres. Bring a drink, a few snacks and a laptop filled with movies. Keep yourself entertained and the time will fly by.
Which airlines fly direct from San Francisco Intl. Airport (SFO) to Knoxville Airport?
You won't find any airlines flying directly between San Francisco Airport and TYS, so be prepared to make at least one stop on your journey. A layover can be a good way to break up a trip!
Are San Francisco Intl. Airport (SFO) to TYS flight tickets cheaper when they're purchased at the last minute?
Booking your trip from San Francisco Intl. Airport (SFO) to Knoxville Airport at the last minute could be your ticket to a great deal. However, it might cost you a whole lot more! If you'd prefer not to take the risk, book well ahead of your departure date. In fact, Expedia has some of the biggest bargains as far ahead as 12 months in advance. If your preferred carrier hasn't released tickets yet, check back regularly as deals are updated on Expedia all the time.

Explore a world of travel with Expedia

*Available to Expedia members.