S$342 Cheap Flights from San Francisco to Santiago

View S$342 flight on Mon, 13 Oct, 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Santiago Intl. Airport (SCL)

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Cheap Flights from San Francisco to Santiago (SFO-SCL)

Prices were available within the past 7 days and start at S$342 for one-way flights and S$650 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, 12 Jan - Thu, 22 Jan
SFO
San Francisco
SCL
Santiago
S$650 Return, found 3 days ago
S$650
Return
found 3 days ago
Select Delta flight, departing Mon, 12 Jan from San Francisco to Santiago, returning Thu, 22 Jan, priced at S$650 found 3 days ago
Delta
Fri, 9 Jan - Thu, 22 Jan
SFO
San Francisco
SCL
Santiago
S$702 Return, found 3 days ago
S$702
Return
found 3 days ago
Select Delta flight, departing Fri, 9 Jan from San Francisco to Santiago, returning Thu, 22 Jan, priced at S$702 found 3 days ago
Copa
Wed, 11 Mar - Wed, 18 Mar
SFO
San Francisco
SCL
Santiago
S$849 Return, found 5 days ago
S$849
Return
found 5 days ago
Select Copa flight, departing Wed, 11 Mar from San Francisco to Santiago, returning Wed, 18 Mar, priced at S$849 found 5 days ago
United
Wed, 11 Mar - Wed, 18 Mar
SFO
San Francisco
SCL
Santiago
S$855 Return, found 5 days ago
S$855
Return
found 5 days ago
Select United flight, departing Wed, 11 Mar from San Francisco to Santiago, returning Wed, 18 Mar, priced at S$855 found 5 days ago
American Airlines
Mon, 12 Jan - Fri, 23 Jan
SFO
San Francisco
SCL
Santiago
S$872 Return, found 3 days ago
S$872
Return
found 3 days ago
Select American Airlines flight, departing Mon, 12 Jan from San Francisco to Santiago, returning Fri, 23 Jan, priced at S$872 found 3 days ago
Delta
Wed, 11 Mar - Wed, 18 Mar
SFO
San Francisco
SCL
Santiago
S$875 Return, found 5 days ago
S$875
Return
found 5 days ago
Select Delta flight, departing Wed, 11 Mar from San Francisco to Santiago, returning Wed, 18 Mar, priced at S$875 found 5 days ago
Delta
Mon, 12 Jan - Tue, 20 Jan
SFO
San Francisco
SCL
Santiago
S$876 Return, found 3 days ago
S$876
Return
found 3 days ago
Select Delta flight, departing Mon, 12 Jan from San Francisco to Santiago, returning Tue, 20 Jan, priced at S$876 found 3 days ago
United
Wed, 11 Mar - Wed, 18 Mar
SFO
San Francisco
SCL
Santiago
S$880 Return, found 5 days ago
S$880
Return
found 5 days ago
Select United flight, departing Wed, 11 Mar from San Francisco to Santiago, returning Wed, 18 Mar, priced at S$880 found 5 days ago
Delta
Mon, 12 Jan - Sat, 24 Jan
SFO
San Francisco
SCL
Santiago
S$882 Return, found 3 days ago
S$882
Return
found 3 days ago
Select Delta flight, departing Mon, 12 Jan from San Francisco to Santiago, returning Sat, 24 Jan, priced at S$882 found 3 days ago
Air Canada
Wed, 11 Mar - Wed, 18 Mar
SFO
San Francisco
SCL
Santiago
S$968 Return, found 5 days ago
S$968
Return
found 5 days ago
Select Air Canada flight, departing Wed, 11 Mar from San Francisco to Santiago, returning Wed, 18 Mar, priced at S$968 found 5 days ago

Find the cheapest month to fly from San Francisco (SFO) to Santiago (SCL)

October is typically the cheapest month to fly

From S$722 - S$1,126 per traveller.

Graph displaying average flight prices per month

San Francisco to Santiago route information
Origin airport
San Francisco Intl.
Destination airport
Arturo Merino Benitez
Return price
S$650
Distance
9474 km

Perfect flights from San Francisco to Santiago

Your Journey from San Francisco to Santiago

Start your unforgettable journey with Expedia. Our broad selection of flights from San Francisco to Santiago caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including avianca, Delta, LATAM Airlines Group, United, Air Canada, Copa, American Airlines. Our selection of flights from San Francisco Intl. to Arturo Merino Benitez caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with San Francisco to Santiago Flights

Experience the joy of finding cheap flights from San Francisco Intl. to Arturo Merino Benitez that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$342 and roundtrip prices from S$650*.
 

Pre-Flight Essentials

Ensure a smooth journey from San Francisco to Santiago with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant Santiago

Picture yourself stepping off the plane in Santiago and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your San Francisco to Santiago Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from San Francisco to Santiago.
 

Beyond the Flight – Exploring Santiago

With Expedia, your adventure extends beyond the flight. Explore Santiago at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from San Francisco to Santiago with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from San Francisco to Santiago with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from San Francisco Intl. Airport (SFO) to SCL?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip flight between San Francisco Intl. Airport (SFO) and Nuevo Pudahuel Airport was S$650. Cheap tickets don't hang around forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Santiago International Airport?
Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the simple instructions on our Customer Service Portal.
How do I find cheap flights from San Francisco Airport to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for San Francisco Airport to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to Santiago International Airport?
The distance is around 9,500 kilometres, so pack your carry-on bag with everything you need to make your journey comfortable. Not sure what to take on board your San Francisco to Santiago flight? A sleep mask, earplugs and a travel pillow are among the essentials.
Which airlines fly direct from SFO to SCL?
Unfortunately, there are no airlines that fly directly between SFO and Santiago International Airport. You'll have to book a flight with one or more stops.
Are San Francisco Airport to Arturo Merino Benitez Airport (SCL) flight tickets cheaper when they're purchased at the last minute?
Late planners can occasionally find a bargain, with some super cheap fares from SFO to Santiago International Airport emerging a few weeks prior to the departure date. If you'd rather plan ahead of time, Expedia compares and updates the best flight deals continuously — as early as 12 months in advance in some cases. It does depend on the carrier though, as not all airlines publish prices that far in advance.

Explore a world of travel with Expedia

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