S$404 Cheap Flights from Panama City to San Diego

View S$404 flight on Thu, 18 Sep, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to San Diego Intl. Airport (SAN)

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Cheap Flights from Panama City to San Diego (PTY-SAN)

Prices were available within the past 7 days and start at S$404 for one-way flights and S$462 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$462 Return, found 4 days ago
S$462
Return
found 4 days ago
Select Delta flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$462 found 4 days ago
United
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$571 Return, found 4 days ago
S$571
Return
found 4 days ago
Select United flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$571 found 4 days ago
United
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$584 Return, found 4 days ago
S$584
Return
found 4 days ago
Select United flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$584 found 4 days ago
United
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$615 Return, found 4 days ago
S$615
Return
found 4 days ago
Select United flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$615 found 4 days ago
United
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$625 Return, found 4 days ago
S$625
Return
found 4 days ago
Select United flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$625 found 4 days ago
United
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$632 Return, found 4 days ago
S$632
Return
found 4 days ago
Select United flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$632 found 4 days ago
Delta
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$645 Return, found 4 days ago
S$645
Return
found 4 days ago
Select Delta flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$645 found 4 days ago
United
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$680 Return, found 4 days ago
S$680
Return
found 4 days ago
Select United flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$680 found 4 days ago
American Airlines
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$726 Return, found 4 days ago
S$726
Return
found 4 days ago
Select American Airlines flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$726 found 4 days ago
Copa
Thu, 18 Sep - Sun, 21 Sep
PTY
Panama City
SAN
San Diego
S$819 Return, found 4 days ago
S$819
Return
found 4 days ago
Select Copa flight, departing Thu, 18 Sep from Panama City to San Diego, returning Sun, 21 Sep, priced at S$819 found 4 days ago

Find the cheapest month to fly from Panama City (PTY) to San Diego (SAN)

September is typically the cheapest month to fly

From S$462 - S$1,367 per traveller.

Graph displaying average flight prices per month

Panama City to San Diego route information
Origin airport
Tocumen Intl.
Destination airport
San Diego Intl.
Return price
S$462
Distance
4658 km
Average flight time
7 hours 29 mins

Perfect flights from Panama City to San Diego

Your Journey from Panama City to San Diego

Start your unforgettable journey with Expedia. Our broad selection of flights from Panama City to San Diego caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including United, Delta, American Airlines, Copa. Our selection of flights from Tocumen Intl. to San Diego Intl. caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with Panama City to San Diego Flights

Experience the joy of finding cheap flights from Tocumen Intl. to San Diego Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$404 and roundtrip prices from S$462*.
 

Pre-Flight Essentials

Ensure a smooth journey from Panama City to San Diego with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant San Diego

Picture yourself stepping off the plane in San Diego and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your Panama City to San Diego Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from Panama City to San Diego.
 

Beyond the Flight – Exploring San Diego

With Expedia, your adventure extends beyond the flight. Explore San Diego at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from Panama City to San Diego with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from Panama City to San Diego with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from PTY to SAN?
Round-trip journeys from Tocumen Intl. Airport (PTY) to San Diego Intl. Airport (SAN) start from S$462. This figure is based on fares advertised within the last 7 days on Expedia for flights departing within the next year --- book now so you don't miss out. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Panama Airport to San Diego Intl. Airport (SAN)?
We get that life can throw the odd curveball, so we've made it as hassle-free as possible for you to cancel your flight online. Just head to the Customer Service Portal and follow the instructions.
How do I find cheap flights from Panama Airport to San Diego Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for PTY to San Diego Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Tocumen Intl. Airport (PTY) to San Diego Airport?
With around 4,700 kilometres separating Tocumen Intl. Airport (PTY) and SAN, your flight will be a long one. Pack wisely and make your time in the air more comfortable. Things like warm clothes and some noise-cancelling headphones can make the biggest difference.
Which airlines fly direct from PTY to San Diego Airport?
Direct flights aren't available, so you'll need to make at least one stop between Panama Airport and San Diego Intl. Airport (SAN). Make the most of the layover time to stretch your legs and take a break.
Are Tocumen Intl. Airport (PTY) to San Diego Airport flight tickets cheaper when they're purchased at the last minute?
It is possible to score a fantastic last-minute deal from Tocumen Intl. Airport (PTY) to SAN, but it's also possible to miss out entirely! As many airlines release prices up to a year in advance, it's worth keeping an eye on fares early and being ready to book when you spot a good bargain. Expedia compares air carrier prices and updates flight deals all the time, so you can be certain you're always seeing the latest offers.

Explore a world of travel with Expedia

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