There are several airlines that operate frequent flights from Milan (MXP) to Brussels (BRU) including

• Lufthansa Cargo with 39 flights a week
• Swiss International Air Lines with 24 flights a week
• KLM with 18 flights a week
• Brussels Airlines with 17 flights a week
• Air France with 14 flights a week

The earliest flight leaves Malpensa Intl. Airport at 08:30 and arrives at Brussels Airport at 10:00. The last flight of the day departs Milan at 22:00 and arrives at Brussels at 23:25.

The flight distance from Milan to Brussels is about 668 km, the shortest flight is 01 hours 25 minutes with Brussels Airlines.

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