There are several airlines that operate frequent flights from Madrid (MAD) to Milan (MXP) including

• IBERIA with 48 flights a week
• Lufthansa Cargo with 32 flights a week
• Air Europa with 29 flights a week
• Vueling Airlines with 27 flights a week
• Air France with 26 flights a week

The earliest flight leaves Adolfo Suarez Madrid Barajas Airport at 07:40 and arrives at Malpensa Intl. Airport at 09:45. The last flight of the day departs Madrid at 20:45 and arrives at Milan at 22:50.

The flight distance from Madrid to Milan is about 1155 km, the shortest flight is 02 hours 05 minutes with Vueling Airlines."

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