There are several airlines that operate frequent flights from New York (LGA) to Manchester (MAN) including

• American Airlines with 11 flights a week
• Air Canada with 10 flights a week
• United Airlines with 8 flights a week
• Delta Air Lines with 4 flights a week
• Virgin Atlantic with 3 flights a week

The earliest flight leaves LaGuardia Airport at 13:59 and arrives at Manchester Airport at 06:45. The last flight of the day departs New York at 18:00 and arrives at Manchester at 08:50.

The flight distance from New York to Manchester is about 5610 km, the shortest flight is 09 hours 44 minutes with Virgin Atlantic.

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