There are several airlines that operate frequent flights from Las Vegas (LAS) to Sao Paulo (GRU) including

• American Airlines with 69 flights a week
• Delta Air Lines with 67 flights a week
• United Airlines with 54 flights a week
• VRG Linhas Areas S.A. - Grupo GOL with 35 flights a week
• LATAM Airlines Brasil with 30 flights a week

The earliest flight leaves McCarran Intl. Airport at 05:01 and arrives at Guarulhos Governor Andre Franco Montoro Intl. Airport at 00:30. The last flight of the day departs Las Vegas at 23:15 and arrives at Sao Paulo at 19:10.

The flight distance from Las Vegas to Sao Paulo is about 10584 km, the shortest flight is 13 hours 55 minutes with United Airlines."

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