There are several airlines that operate frequent flights from Houston (IAH) to Rome (FCO) including

• United Airlines with 167 flights a week
• American Airlines with 65 flights a week
• Delta Air Lines with 53 flights a week
• Lufthansa Cargo with 42 flights a week
• KLM with 33 flights a week

The earliest flight leaves George Bush Intercontinental Airport at 08:26 and arrives at Fiumicino Leonardo da Vinci Intl. Airport at 07:15. The last flight of the day departs Houston at 23:05 and arrives at Rome at 23:55.

The flight distance from Houston to Rome is about 9371 km, the shortest flight is 11 hours 55 minutes with United Airlines."

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