There are several airlines that operate frequent flights from Sao Paulo (GRU) to Orlando (MCO) including

• LATAM Airlines Brasil with 44 flights a week
• COPA Airlines with 43 flights a week
• American Airlines with 42 flights a week
• VRG Linhas Areas S.A. - Grupo GOL with 16 flights a week
• Delta Air Lines with 12 flights a week

The earliest flight leaves Guarulhos Governor Andre Franco Montoro Intl. Airport at 10:30 and arrives at Orlando Intl. Airport at 06:00. The last flight of the day departs Sao Paulo at 23:55 and arrives at Orlando at 19:30.

The flight distance from Sao Paulo to Orlando is about 6906 km, the shortest flight is 08 hours 55 minutes with United Airlines."

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