There are several airlines that operate frequent flights from Frankfurt (FRA) to Barcelona (BCN) including

• Lufthansa Cargo with 348 flights a week
• Swiss International Air Lines with 62 flights a week
• Air Berlin with 51 flights a week
• KLM with 38 flights a week
• Brussels Airlines with 36 flights a week

The earliest flight leaves Frankfurt Intl. Airport at 07:05 and arrives at Barcelona Intl. Airport at 09:05. The last flight of the day departs Frankfurt at 21:20 and arrives at Barcelona at 23:20.

The flight distance from Frankfurt to Barcelona is about 1099 km, the shortest flight is 02 hours with Oman Air."

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