There are several airlines that operate frequent flights from Detroit (DTW) to Portland (PDX) including

• Delta Air Lines with 196 flights a week
• with 54 flights a week
• United Airlines with 47 flights a week
• Alaska Airlines with 37 flights a week
• American Airlines with 28 flights a week

The earliest flight leaves Detroit Metropolitan Wayne County Airport at 15:50 and arrives at Portland Intl. Airport at 17:36. The last flight of the day departs Detroit at 20:25 and arrives at Portland at 22:23.

The flight distance from Detroit to Portland is about 3150 km, the shortest flight is 04 hours 46 minutes with .

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