What is Santa Lucia like?

Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Lucia?

Based on Expedia customer reviews, Giuggiulena Villa is the highest ranked property in Santa Lucia. This affittacamere offers a bar and a rooftop terrace. Other top choices in the neighbourhood include Caportigia Boutique Hotel and La casa di Aneupe .

How many hotels will I find in Santa Lucia?

Expedia has 267 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

Top 10 Santa Lucia Hotels of 2025

Top 10 Hotels in Santa Lucia

Enjoy the ocean view from this balcony with a table, chairs, and a potted plant.

"Fantastic hotel with great facilities and very friendly and helpful staff. Breakfast was very tasty (and lovely to eat on the terrace overlooking the sea). Beautiful big room with a balcony right above the sea. A lovely calm atmosphere about the whole place. It was great to be able to go downstairs for a swim with islands to sit on just at the back of the hotel. The upper floor where the loungers were was perfect and a very relaxing place to sit after exploring busy Ortigia. Sabrina also let us...

includes taxes & fees

4 Aug - 5 Aug

Relax in a serene outdoor space with a comfortable sofa, tables, and lush greenery.

"Perfect place"

includes taxes & fees

24 Jul - 25 Jul

Relax in a stylish room with a flat-screen TV, desk, and comfortable bed.

"Very welcoming staff "

includes taxes & fees

21 Jul - 22 Jul

Enjoy the urban view from this balcony with a table and potted plant, overlooking the city's diverse architecture.

"This is an AMAZING AND EXCEPTIONAL property! Tucked away in a residential area with just a three minute walk to the bus stop. The hotel is beautifully furnished and modern. The rooms are spacious and inviting. This boutique hotel feels like a luxury five star hotel. I definitely want to come back to Cagliari, and when I do, rest assured I will be staying at Nemo. Also breakfast on the roof top is amazing! "

Enjoy the view from this balcony with a table, chair, and potted plant.

"Ana, una muy buena anfitriona. Todo detalle impecable. Habitación amplia, limpia y equipada. El lugar en el punto justo. El desayuno espectacular. Dulce, salado, exquisito. Para volver. "

Relax in a serene space with a large bed, bedside table, and comfortable chair.

"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."

includes taxes & fees

24 Jul - 25 Jul

Stunning historic building with ornate detailing and central entrance.

"Good proximity to Ortigia. "

Guests can enjoy a serene ocean view from the terrace, featuring a comfortable chair and bean bag.

"Wonderful property, excellent staff and the most amazing view from the apartment"

includes taxes & fees

19 Aug - 20 Aug

Enjoy a serene harbor view from this room, featuring a table, chair, and lamp.

"Nice location to where dining options and sites to see are numerous "

Enjoy a spacious room with a large mirror, a comfortable bed, and a desk area with a flat-screen TV.

"It was easy to register, clean and a good location. Not to mention the free croissant in the morning!"

includes taxes & fees

24 Jul - 25 Jul

Enjoy panoramic views of the city from this rooftop retreat, featuring a seating area with a potted plant and cityscape vistas.

"Just stay somewhere else, plain and simple."

includes taxes & fees

21 Jul - 22 Jul

Stunning staircase leads to a spacious upper floor with a balcony.

includes taxes & fees

28 Jul - 29 Jul

Relax in this inviting space with a comfortable bed and a charming bedside tray featuring a potted plant and refreshments.

"Good location, very modern clean accommodation."

includes taxes & fees

23 Jul - 24 Jul

Relax in a serene courtyard surrounded by lush greenery and a shaded pergola.

"Nice quirky place to stay in Siracusa located conveniently for everything you need and very professional staff "

Enjoy a relaxing meal or unwind with a view of the marina from this balcony.

"Very helpful host who shared lots of recommendations and tips. Great location and very nice rooms."

includes taxes & fees

3 Aug - 4 Aug

includes taxes & fees

21 Jul - 22 Jul

Hotel del Campo features a traditional architectural style with a symmetrical facade and arched doorways.

"Convenient location for Syracuse town, but in a scruffy area and the whole property is looking tired. Breakfast was adequate. The owner was charming and happy to help."

includes taxes & fees

22 Jul - 23 Jul

includes taxes & fees

23 Jul - 24 Jul

Boats docked at the marina, adjacent to a lively waterfront area with buildings and illuminated windows.

"Location is fine, rooms are clean and well kept but the place feels a bit abandoned and unloved. Staff is friendly and helpful, but all services (check in, breakfast) are in another hotel across the road, which means there is no security or supervision at all. We were given a room without balcony, which was clearly offered in their listing. Without much ado they gave us a better room, saying they put 'the wrong photo' up and it had to be changed. The wrong photo is still up there, so...

includes taxes & fees

27 Jul - 28 Jul

Enjoy cooking in this well-equipped kitchen with a gas stove, sink, and ample storage.

"Good location."

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

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Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

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Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

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Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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Top Santa Lucia Hotel Reviews

Caportigia Boutique Hotel

10/10 Excellent

"Perfect place"

Palazzo Artemide - VRetreats

10/10 Excellent

"Every traveller in the last 4 years or so will have noticed the insanely abusive increase in worldwide accomodation pricing often doubling or tripling what rooms cost 5 years ago. After 20 days of travel between turkey and sicily i would say this hotel was by far the greatest value for the money spent. Impeccably curated in every detail, elegant decoration. Comfortable rooms and cleanliness. The restaurant is great too. I would stay here again every time i return to Siracusa. Highly recommend. "

Algila' Ortigia Charme Hotel

10/10 Excellent

"The rooms are stunningly decorated, comfortable beds, great air conditioning, very clean. The common area are also breathtaking. The staff are also amizng and helped us book transportation and arranged a beach club day. This location is also close to all shopping and great dinning. The included breakfast was also great. "

Hotel Armonia Noto Marina e Spa

2/10 Terrible

"Terrible experience. We were two couples and booked 2 double rooms. 2 hours before checking in we received a link to go to a different a accommodation location than the one we booked with no explanation. It was a residence not a hotel. No Reception at new location, nowhere to buy a coffee or water (not even a vending machine), beach was 15 minutes drive by car unlike the hotel we booked. Breakfast was served in a run-down coffee shop15 minutes drive from residence and food selection was dismal. Luckily we had a car. Furniture in balcony consisted of a 2 rusty chairs and table. Defective TV in room only worked a few minutes then stopped. During our stay we noted that other guests at the Residence also experienced the same scam that we suffered. Shame on the Management."

Grande Albergo Alfeo

10/10 Excellent

"Charming Sicilian Hotel within walking distance to bustling Ortiga. Lots of restaurants and shops nearby. Friendly staff and delicious daily breakfast with made to order cafe. Bonus- complimentary granita provided to hotel guests daily in the lobby. A/C is a welcome respite to escape the hot summer temps. "

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Top 10 Hotels in Santa Lucia

Giuggiulena Villa