Midtown
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its great live music.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Best of St. Louis Small Group Tour w/ Arch & River Cruise
Dinner Detective True Crime Murder Mystery Show - St. Louis, MO
St. Louis Premium Driving Tour with Boat Ride & Arch
St Louis Self-Guided Driving and Walking Audio Tour
Gateway Arch National Park Self Guided Audio Walking Tour
Top hotels in Midtown
Element St. Louis Midtown
The room was spacious, and the staff were as friendly and helpful as any I have ever met.
Reviewed on 16 Dec, 2025
Hyatt Regency St. Louis at The Arch
It was fast and were able to accommodate a joining room for us.
Reviewed on 20 Dec, 2025
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Breakfast area was small and crowded - did not help to have children and some teenagers on their own and not exactly being quiet.
Reviewed on 19 Dec, 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Good
Reviewed on 16 Dec, 2025
Drury Plaza Hotel St. Louis at the Arch
All is perfect except room cleanse
Reviewed on 18 Dec, 2025
21C Museum Hotel St Louis
Clean room, nice linens, great view!
Reviewed on 20 Dec, 2025
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
