Seneca Hotels from S$74

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Our top choices for Seneca hotels

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (642)
"The stay was amazing "
United States
Tabatha
The price is S$131
includes taxes & fees
11 Jan - 12 Jan, 2026
Best Western Seneca-Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (52)
"The place was absolutely magnificent."
United States
David
The price is S$182
includes taxes & fees
26 Jan - 27 Jan, 2026
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is S$162
includes taxes & fees
31 Dec - 1 Jan, 2026
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (664)
"Great place to stay"
United States
Jose
The price is S$169
includes taxes & fees
15 Jan - 16 Jan, 2026
Hampton Inn & Suites Seneca-Clemson Area

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (665)
"Friendly check in, clean room."
United States
connie
The price is S$111
includes taxes & fees
4 Jan - 5 Jan, 2026
Quality Inn Seneca Clemson Area US-123

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1000)
"Great place to stay. "
United States
Gene
The price is S$174
includes taxes & fees
26 Jan - 27 Jan, 2026
Lakeside Lodge Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (798)
"Staff is amazing, hotel and amenities are great. "
United States
Shannon
The price is S$141
includes taxes & fees
25 Jan - 26 Jan, 2026
Tru by Hilton Seneca Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (721)
"Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. "
United States
Teresa
The price is S$103
includes taxes & fees
28 Dec - 29 Dec
Days Inn by Wyndham Seneca / Clemson Area

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
Pendleton
10.0 out of 10, Exceptional, (78)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
The price is S$224
includes taxes & fees
2 Jan - 3 Jan, 2026
Liberty Hall Bed and Breakfast

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (387)
"Staff was very friendly and accommodating "
United States
Lisa
The price is S$74
includes taxes & fees
10 Jan - 11 Jan, 2026
Quality Inn & Suites Easley - Greenville

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (756)
"Easy access from the highway lot of restaurants around the hotel and staff is very friendly"
United States
brian
The price is S$107
includes taxes & fees
26 Jan - 27 Jan, 2026
Baymont by Wyndham Easley/Greenville

Days Inn by Wyndham Easley/Greenville/Clemson Area

Days Inn by Wyndham Easley/Greenville/Clemson Area
2.0 star property
Easley
6.2 out of 10, (822)
"Friendly staff"
United States
Tina
The price is S$95
includes taxes & fees
27 Dec - 28 Dec
Days Inn by Wyndham Easley/Greenville/Clemson Area

Frank Howard 111 Farmhouse

Frank Howard 111 Farmhouse
3.0 star property
Clemson
9.8 out of 10, Exceptional, (10)
"Great stay "
United States
Johnny
The price is S$319
includes taxes & fees
13 Jan - 14 Jan, 2026
Frank Howard 111 Farmhouse

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very good, (1002)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1002)
"Clean room and staff were great’"
United States
Audrey
The price is S$120
includes taxes & fees
29 Dec - 30 Dec
Best Western Plus Clemson Hotel & Conference Center

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (743)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is S$238
includes taxes & fees
27 Dec - 28 Dec
The Shepherd Hotel Downtown Clemson

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (523)
"Overall, great stay!"
United States
Lynn
The price is S$170
includes taxes & fees
27 Dec - 28 Dec
Courtyard Marriott Clemson

Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (950)
"Had a great stay at this hotel. Conveniently located near restaurants. "
United States
Kelly
The price is S$168
includes taxes & fees
10 Jan - 11 Jan, 2026
Holiday Inn Express & Suites Clemson by IHG

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (961)
"Great place to stay!"
United States
Mindi
The price is S$212
includes taxes & fees
28 Dec - 29 Dec
Clemson University's James F. Martin Inn

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very good, (1002)
"Great stay "
United States
Linda
The price is S$146
includes taxes & fees
11 Jan - 12 Jan, 2026
Comfort Inn & Suites Clemson - University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most.

Downtown

If you're spending some time in Downtown, Seneca Historic District and Oconee County Library Seneca Branch are top sights worth seeing.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and Keowee Key Golf Course.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Keowee Reservoir and Oconee County Library Seneca Branch.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Seneca Historic District are some notable places to visit nearby.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel offers free breakfast and free parking. Traveller reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Quality Inn Seneca Clemson Area US-123 is a top hotel for people travelling with their pets, and offers a seasonal outdoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Days Inn by Wyndham Seneca / Clemson Area and Lakeside Lodge Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Quality Inn Seneca Clemson Area US-123: Features daily, a seasonal outdoor pool and free self parking. Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 288 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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