
Santa Cruz Holidays
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Top hotels in Santa Cruz

Camino Real Hotel
Reviewed on 16 Jul, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Reviewed on 21 Jun, 2025

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Reviewed on 7 Jul, 2025
Frequently asked questions
Popular places to visit
Plaza Principal San Jose de Chiquitos
Learn about the local history of San Jose de Chiquitos with a stop at Plaza Principal San Jose de Chiquitos. Amble around the area's forests or visit its churches.
What to do in Santa Cruz

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

3D/2N Getaway on the Che Guevara Route in Bolivia
More trip options
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.