Santa Cruz Holidays

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    Better together

    Save up to S$134 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Santa Cruz

Camino Real Hotel
Camino Real Hotel
4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is S$179 per night from 12 Aug to 13 Aug
S$179
12 Aug - 13 Aug
8.8/10 Excellent! (388 reviews)
"Great experience . Cannot say enough about the hotel. I will definitely return ."

Reviewed on 8 Jul, 2025

Camino Real Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is S$134 per night from 13 Aug to 14 Aug
S$134
13 Aug - 14 Aug
8.8/10 Excellent! (320 reviews)
"Always an amazing hotel"

Reviewed on 21 Jun, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
The price is S$132 per night from 17 Jul to 18 Jul
S$132
17 Jul - 18 Jul
9/10 Wonderful! (244 reviews)
"Location, surrounding, quietness, good service"

Reviewed on 7 Jul, 2025

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
See all 270 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Guarani Nandereko Nomai Art and Culture Center

You can enjoy some culture when you stop by Guarani Nandereko Nomai Art and Culture Center in Santa Cruz. While in the area, you can find time to visit its shops.

Guarani Nandereko Nomai Art and Culture Center

What to do in Santa Cruz

Wildlife rescue center and preservation park

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

S$109
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
Fuerte de Samaipata, Bolivia

Samaipata Fort & Caves Tour (1 Full Day)

S$332
per adult
Samaipata Fort & Caves Tour (1 Full Day)
Trekking through the area of ​​​​the last armed struggle of Che Guevara.

3D/2N Getaway on the Che Guevara Route in Bolivia

S$1,165
per adult
3D/2N Getaway on the Che Guevara Route in Bolivia
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz holiday package cost?
You'll find cheap prices on Expedia for your Santa Cruz break. However, a range of factors like the hotel choice, length of stay and season will determine how much your holiday to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
February, April and May are the best times to look for cheap Santa Cruz holiday packages. Opting to travel in quieter months means you can typically find lower prices on hotels and flights.
How many days is enough for Santa Cruz?
Typically, a handful of days is enough to tick off the main sights during your Santa Cruz holiday. However, if you prefer to have some time to kick back or take day tours, think about extending your itinerary.
Is it worth booking a holiday package to Santa Cruz?
Santa Cruz is a good holiday destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're travelling with the family or getting away with friends, a Santa Cruz holiday promises a good time for everyone.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some tempting Santa Cruz package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or look for Santa Cruz package deals in the off-peak season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your holiday package as early as possible.
Is it cheaper to book a Santa Cruz holiday as a package?
You can enjoy significant savings on your Santa Cruz escape by booking a personalised holiday package. Click on the "Package" heading, then enter your travel dates and destination to browse some great hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a holiday package to Santa Cruz?
If you're considering an impromptu Santa Cruz adventure, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Cruz?

  1. Choose your dates: What you want to do in Santa Cruz and your favourite season will help you decide when to get away.
  2. Work out your budget: Make sure you have enough money to pay for everything from transportation and dining out to experiences and flights. Your hotel will probably be the biggest expense during your trip to Santa Cruz.
  3. Work out your trip length: Consider how much time you want to spend discovering Santa Cruz. Plan your days so you can get to all the experiences and attractions you're interested in without rushing.
  4. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to choose a Santa Cruz holiday package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.