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Check Santa Cruz hotel prices

Tonight
22 Nov - 23 Nov
Tomorrow night
23 Nov - 24 Nov
This weekend
22 Nov - 24 Nov

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Top 10 trending Santa Cruz hotels

Hotel Palpa Lines
Free WiFi
Hotel Palpa Lines
2.0 star property
Hotel Palpa Lines
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
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Frequently asked questions

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes, most room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What are the top places to visit in Santa Cruz?

A favourite place to visit is Cerro Bodegayoc. Additionally, you'll find Nazca Lines in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually March and April, with an average temperature of 22°C, while the coldest months are August and July, with an average of 19°C. Average annual precipitation for Santa Cruz is 50 mm.