Santa Cruz Hotels from S$16

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Santa Cruz hotels

La Casita de mi Abuela

3.0 star property
6.8 out of 10, (3)
"Excelente lugar para disfrutar la naturaleza, la atención es súper y las vistas geniales. Súper recomendado "
La Casita de mi Abuela

GRAN HOTEL

2.0 star property
The price is S$31
22 Jul - 23 Jul
GRAN HOTEL

hostal kactus

1.0 star property
The price is S$16
1 Aug - 2 Aug
hostal kactus

Oro Andino Lodge

2.5 star property
The price is S$198
3 Aug - 4 Aug
Oro Andino Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santa Cruz

Venture to sights like Huascaren National Park and Punta Union as you discover Santa Cruz.

Photo by nevin xavier
Open Photo by nevin xavier

Top Santa Cruz Hotel Reviews

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Santa Cruz Eco Lodge is one of the top choices for your stay based on our traveller data. This lodge offers free breakfast and free parking. Other good choices for your stay in the area are Oro Andino Lodge and La Casita de mi Abuela. See all available top hotels, or vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What is the top LGBTQ-friendly place to stay in Santa Cruz?

Santa Cruz Eco Lodge is a top LGBTQ-friendly lodge that features free breakfast and free parking. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's it like staying in Santa Cruz?

Visitors to Santa Cruz will definitely find plenty to explore and enjoy. There are 14 hotels and other accommodation options in the surrounding area. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

A couple of favourite places to visit are Huascaren National Park and Punta Union. You'll also find Lake Paron and Cañón del Pato in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

What's the weather like in Santa Cruz?

The hottest months are usually August and July, with an average temperature of 12°C, while the coldest months are July and August, with an average of 12°C. The rainiest months in Santa Cruz are March, January, December and February, with each month seeing an average of 255 mm of rainfall.