Sanibel Island Southern Beach

Sanibel Island Southern Beach
Photo by Bonnie Bareford
Photo by Bonnie Bareford
Photo by Anthony Ball
Photo by Anthony Ball
Photo by Sérgio Veludo
Photo by Sérgio Veludo
Photo by Sérgio Veludo
Photo by Sérgio Veludo

Popular places to visit

Sanibel Historical Museum and Village

Sanibel Historical Museum and Village

You can spend time studying the exhibits at Sanibel Historical Museum and Village during your trip to Sanibel. Wander through the beautiful beaches and seaside in this family-friendly area.

Sanibel Historical Museum and Village
Periwinkle Way

Periwinkle Way

The island’s spine is also its commercial hub. Drive or bike the road’s length to find attractions and discover many stores and restaurants.

Periwinkle Way
Clinic for the Rehabilitation of Wildlife

Clinic for the Rehabilitation of Wildlife

See the exotic and native animals who call Clinic for the Rehabilitation of Wildlife home during your trip to Sanibel. Wander the beautiful beaches or discover the beautiful sunsets in this family-friendly area.

Clinic for the Rehabilitation of Wildlife
J. N. Ding Darling National Wildlife Refuge

J. N. Ding Darling National Wildlife Refuge

See almost anything that flies, swims or crawls in Florida in this protected area. Become acquainted with wildlife while learning about varied species.

J. N. Ding Darling National Wildlife Refuge
Sanibel Moorings Botanical Gardens

Sanibel Moorings Botanical Gardens

Enjoy the beautiful sunsets and explore Sanibel Moorings Botanical Gardens, a lovely green space in Sanibel. Wander through the beautiful beaches and seaside in this family-friendly area.

Sanibel Moorings Botanical Gardens

Bailey - Matthews Shell Museum

You can spend time exploring the galleries in Bailey - Matthews Shell Museum during your travels in Sanibel. Amble around this family-friendly area's beautiful beaches and enjoy its lively bars.

Bailey - Matthews Shell Museum

Top Sanibel Island Southern Beach Hotel Deals

Marriott Sanibel Harbour Resort & Spa
Marriott Sanibel Harbour Resort & Spa
4 out of 5
17260 Harbour Pointe Dr, Fort Myers, FL
Marriott Sanibel Harbour Resort & Spa
THE Palmview AND Sandpiper Inns
THE Palmview AND Sandpiper Inns
3.5 out of 5
706 and 720 Donax Street, Sanibel, FL
THE Palmview AND Sandpiper Inns
See all 10,767 properties in Sanibel Island Southern Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.